Leptin and fractalkine: Novel subcutaneous cytokines in burn injury

Leptin and fractalkine: Novel subcutaneous cytokines in burn injury

Burn damage is a pathology underpinned by progressive and aberrant irritation. It’s a main medical problem to survival and high quality of life. Whereas burn damage’s advanced native and disseminating pathological processes in the end stem from native tissue injury, thus far comparatively few research have tried to characterise the native inflammatory mediator profile.
Right here, cytokine content material and related transcriptional modifications have been measured in rat pores and skin for 3 hours instantly following induction of a scald-type (60°C, 2 minutes) burn damage mannequin. Leptin (p=0.0002) and fractalkine (p=0.0478) concentrations have been considerably elevated post-burn above pre-burn and management website values, coinciding with the event of burn website oedema and differential expression of leptin mRNA (p=0.0004).
Additional, gene sequencing enrichment evaluation indicated cytokine-cytokine receptor interplay (p=1.45×10-6). Subsequent behavioural research demonstrated that, following subcutaneous injection into the dorsum of the paw, each leptin and fractalkine induced mechanical allodynia, warmth hyperalgesia and the recruitment of macrophages.
That is the primary report of leptin’s elevation particularly on the burn website and the primary report of fractalkine’s elevation in any tissue post-burn which, along with the useful findings, requires exploration of the affect of those cytokines on ache, irritation and burn wound development. Moreover focusing on these signalling molecules represents a therapeutic potential as early formative mediators of those pathological processes.

Hepcidin Will increase Cytokines in Alzheimer’s Illness and Down’s Syndrome Dementia: Implication of Impaired Iron Homeostasis in Neuroinflammation

The liver-derived hormone hepcidin, a member of the defensin household of antimicrobial peptides, performs an vital position in host protection and innate immunity as a result of its broad antibacterial and antiviral properties. Ferritin, an iron storage protein is usually related to iron deficiency, hypoferritinemia, hypoxia, and immune issues, that are all vital issues for systemic an infection in Alzheimer’s illness (AD) and Down’s syndrome (DS) dementia.
Serum and autopsy mind samples have been collected from AD, DS and age-matched management topics. Serum samples have been analyzed with ELISA for ferritin, hepcidin and IL-6. Moreover, autopsy mind sections have been assessed by immunohistochemistry for iron-related and inflammatory proteins. A major enhance in serum hepcidin ranges was present in DS, in comparison with controls and AD topics (p < 0.0001).
Hepcidin protein was seen within the epithelial cells of choroid plexus, meningeal macrophages and within the astrocytes near the endothelium of blood vessels. Hepcidin co-localized with IL-6, indicating its anti-inflammatory properties. We discovered vital correlation between hypoferritinemia and elevated ranges of serum hepcidin in AD and DS. Hepcidin might be transported through macrophages and nearly all of the vesicular hepcidin enters the mind through a compromised blood mind barrier (BBB). Our findings present additional perception into the molecular implications of the altered iron metabolism in acute irritation, and may help in the direction of the event of preventive methods and novel remedies within the combat towards neuroinflammation.
 Leptin and fractalkine: Novel subcutaneous cytokines in burn injury

Case Report: A Case of Trimethoprim/Sulfamethoxazole-Triggered Hypotensive Shock: Cytokine Launch Syndrome Associated to Immune Checkpoint Inhibitors and Drug-Induced Hypersensitivity Syndrome

At the moment, only some stories exist on the cytokine launch syndrome (CRS) as one of many extreme immune-related adversarial occasions (irAEs) induced by immune checkpoint inhibitors (ICIs). Notably, it is extremely uncommon that grade Four CRS associated to ICI remedy overlaps with the drug-induced hypersensitivity syndrome (DiHS). A 46-year outdated girl with metastatic kidney most cancers had grade three interstitial pneumonitis induced by 4 cycles of mixture remedy of anti-programmed death-1 and anti-cytotoxic T lymphocyte-Four antibodies after proper cytoreductive nephrectomy.
Prophylactic administration of trimethoprim/sulfamethoxazole (TMP/SMX) was began concomitantly with prednisolone remedy to deal with the interstitial pneumonitis. She developed hypotensive shock when decreasing the dosage of prednisolone, and required intubation and air flow utilizing vasopressors on the intensive care unit.
She subsequently exhibited outstanding leukocytosis and an elevated stage of C-reactive protein, suggesting markedly elevated cytokine ranges. Curiously, facial edema and erythema elevated in affiliation with pyrexia, leukocytosis, liver dysfunction, and renal failure, suggesting that she developed DiHS. She obtained hemodialysis 3 times, a plasma alternate, and anti-interleukin-6 remedy to deal with extreme renal dysfunction, a thrombotic thrombocytopenic purpura-suspected situation, and potential grade Four CRS, respectively.

Mouse Dedicator of cytokinesis protein 8 (Dock8)

1-CSB-YP807451MO1
  • EUR 586.00
  • EUR 299.00
  • EUR 2172.00
  • EUR 900.00
  • EUR 1442.00
  • EUR 382.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse Dedicator of cytokinesis protein 8(Dock8),partial expressed in Yeast

Mouse Dedicator of cytokinesis protein 8 (Dock8)

1-CSB-EP807451MO
  • EUR 505.00
  • EUR 265.00
  • EUR 1827.00
  • EUR 766.00
  • EUR 1218.00
  • EUR 335.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse Dedicator of cytokinesis protein 8(Dock8),partial expressed in E.coli

Mouse Dedicator of cytokinesis protein 8 (Dock8)

1-CSB-EP807451MO1
  • EUR 505.00
  • EUR 265.00
  • EUR 1827.00
  • EUR 766.00
  • EUR 1218.00
  • EUR 335.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse Dedicator of cytokinesis protein 8(Dock8),partial expressed in E.coli

Dedicator of Cytokinesis 2 (DOCK2) Antibody

20-abx126888
  • EUR 411.00
  • EUR 592.00
  • 100 ul
  • 200 ul

Dedicator of Cytokinesis 2 (DOCK2) Antibody

20-abx129016
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Dedicator of Cytokinesis 4 (DOCK4) Antibody

20-abx129252
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Dedicator of Cytokinesis 1 (DOCK1) Antibody

20-abx112009
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Dedicator of Cytokinesis 2 (DOCK2) Antibody

20-abx112010
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Dedicator of Cytokinesis 3 (DOCK3) Antibody

20-abx112011
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Dedicator of Cytokinesis 3 (DOCK3) Antibody

20-abx313603
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Dedicator of Cytokinesis 1 (DOCK1) Antibody

20-abx102732
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Dedicator of Cytokinesis 2 (DOCK2) Antibody

20-abx149900
  • EUR 425.00
  • EUR 342.00
  • 100 ug
  • 50 ug

Dedicator of Cytokinesis 1 (DOCK1) Antibody

abx147652-100ug 100 ug
EUR 439

Dedicator of Cytokinesis 1 (DOCK1) Antibody

20-abx014419
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Dedicator of Cytokinesis 1 (DOCK1) Antibody

abx431929-200ul 200 ul
EUR 384

Dedicator Of Cytokinesis 1 (DOCK1) Antibody

20-abx211608
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Dedicator Of Cytokinesis 3 (DOCK3) Antibody

20-abx176110
  • EUR 1205.00
  • EUR 578.00
  • 1 mg
  • 200 ug

Dedicator Of Cytokinesis 3 (DOCK3) Antibody

20-abx172052
  • EUR 857.00
  • EUR 439.00
  • 1 mg
  • 200 ug

Dedicator Of Cytokinesis 4 (DOCK4) Antibody

20-abx172053
  • EUR 857.00
  • EUR 439.00
  • 1 mg
  • 200 ug

Dedicator Of Cytokinesis 1 (DOCK1) Antibody

abx330938-100ul 100 ul
EUR 425

Dedicator Of Cytokinesis 2 (DOCK2) Antibody

20-abx326569
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Dedicator Of Cytokinesis 1 (DOCK1) Antibody

20-abx325559
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Dedicator Of Cytokinesis 1 (DOCK1) Antibody

20-abx333995
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Human Dedicator of cytokinesis protein 8 (DOCK8)

1-CSB-YP836734HU
  • EUR 504.00
  • EUR 265.00
  • EUR 1832.00
  • EUR 763.00
  • EUR 1216.00
  • EUR 334.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Dedicator of cytokinesis protein 8(DOCK8),partial expressed in Yeast

Human Dedicator of cytokinesis protein 8 (DOCK8)

1-CSB-YP836734HUb0
  • EUR 504.00
  • EUR 265.00
  • EUR 1832.00
  • EUR 763.00
  • EUR 1216.00
  • EUR 334.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Dedicator of cytokinesis protein 8(DOCK8),partial expressed in Yeast

Dedicator of Cytokinesis Protein 5 (DOCK5) Antibody

abx122686-100ug 100 ug
EUR 391

Dedicator of Cytokinesis Protein 5 (DOCK5) Antibody

20-abx311377
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Human Dedicator Of Cytokinesis 3 (DOCK3) Protein

20-abx653130
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Dedicator Of Cytokinesis 1 (DOCK1) Protein

20-abx066282
  • EUR 648.00
  • EUR 272.00
  • EUR 1998.00
  • EUR 773.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Dedicator of Cytokinesis Protein 10 (DOCK10) Antibody

abx145342-100ug 100 ug
EUR 391

Human Dedicator Of Cytokinesis 2 (DOCK2) Protein

20-abx166509
  • EUR 648.00
  • EUR 272.00
  • EUR 1943.00
  • EUR 759.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Dedicator Of Cytokinesis 4 (DOCK4) Protein

20-abx168105
  • EUR 648.00
  • EUR 272.00
  • EUR 1998.00
  • EUR 773.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Dedicator of Cytokinesis Protein 10 (DOCK10) Antibody

20-abx301562
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Mouse Dedicator of cytokinesis protein 9, Dock9 ELISA KIT

ELI-26224m 96 Tests
EUR 865

Mouse Dedicator of cytokinesis protein 4, Dock4 ELISA KIT

ELI-26847m 96 Tests
EUR 865

Mouse Dedicator of cytokinesis protein 5, Dock5 ELISA KIT

ELI-26848m 96 Tests
EUR 865

Mouse Dedicator of cytokinesis protein 1, Dock1 ELISA KIT

ELI-47076m 96 Tests
EUR 865

Mouse Dedicator of cytokinesis protein 2, Dock2 ELISA KIT

ELI-47799m 96 Tests
EUR 865

Mouse Dedicator of cytokinesis protein 7, Dock7 ELISA KIT

ELI-32144m 96 Tests
EUR 865

Mouse Dedicator of cytokinesis protein 6, Dock6 ELISA KIT

ELI-32830m 96 Tests
EUR 865

Mouse Dedicator of cytokinesis protein 10, Dock10 ELISA KIT

ELI-31732m 96 Tests
EUR 865

Mouse Dedicator of cytokinesis protein 3, Dock3 ELISA KIT

ELI-09219m 96 Tests
EUR 865

Mouse Dedicator of cytokinesis protein 8, Dock8 ELISA KIT

ELI-09684m 96 Tests
EUR 865

Dedicator of Cytokinesis 3 (DOCK3) Antibody (HRP)

20-abx313604
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Dedicator of Cytokinesis 3 (DOCK3) Antibody (FITC)

20-abx313605
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Dedicator of Cytokinesis 3 (DOCK3) Antibody (Biotin)

20-abx313606
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Dedicator Of Cytokinesis 1 (DOCK1) Antibody (HRP)

20-abx335295
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Dedicator Of Cytokinesis 1 (DOCK1) Antibody (FITC)

20-abx335296
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Dedicator Of Cytokinesis 1 (DOCK1) Antibody (Biotin)

20-abx335297
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Human Dedicator Of Cytokinesis Protein 6 (DOCK6) ELISA Kit

abx386963-96tests 96 tests
EUR 911

Human Dedicator Of Cytokinesis Protein 7 (DOCK7) ELISA Kit

abx386964-96tests 96 tests
EUR 911

Human Dedicator Of Cytokinesis Protein 8 (DOCK8) ELISA Kit

abx386965-96tests 96 tests
EUR 911

Human Dedicator Of Cytokinesis Protein 9 (DOCK9) ELISA Kit

abx386966-96tests 96 tests
EUR 911

Human Dedicator Of Cytokinesis Protein 1 (DOCK1) ELISA Kit

abx259546-96tests 96 tests
EUR 911

Human Dedicator of cytokinesis protein 6, DOCK6 ELISA KIT

ELI-26222h 96 Tests
EUR 824

Human Dedicator of cytokinesis protein 9, DOCK9 ELISA KIT

ELI-26223h 96 Tests
EUR 824

Human Dedicator of cytokinesis protein 2, DOCK2 ELISA KIT

ELI-46901h 96 Tests
EUR 824

Human Dedicator of cytokinesis protein 10, DOCK10 ELISA KIT

ELI-47075h 96 Tests
EUR 824

Human Dedicator of cytokinesis protein 3, DOCK3 ELISA KIT

ELI-32143h 96 Tests
EUR 824

Human Dedicator of cytokinesis protein 7, DOCK7 ELISA KIT

ELI-31733h 96 Tests
EUR 824

Human Dedicator of cytokinesis protein 4, DOCK4 ELISA KIT

ELI-08843h 96 Tests
EUR 824

Human Dedicator of cytokinesis protein 1, DOCK1 ELISA KIT

ELI-09218h 96 Tests
EUR 824

Human Dedicator of cytokinesis protein 5, DOCK5 ELISA KIT

ELI-09220h 96 Tests
EUR 824

Human Dedicator of cytokinesis protein 8, DOCK8 ELISA KIT

ELI-09221h 96 Tests
EUR 824

Dedicator Of Cytokinesis 1 (DOCK1) Polyclonal Antibody (Human)

4-PAG175Hu01
  • EUR 247.00
  • EUR 2510.00
  • EUR 625.00
  • EUR 310.00
  • EUR 214.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 1 (DOCK1)

Dedicator Of Cytokinesis 2 (DOCK2) Polyclonal Antibody (Human)

4-PAG182Hu01
  • EUR 247.00
  • EUR 2510.00
  • EUR 625.00
  • EUR 310.00
  • EUR 214.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 2 (DOCK2)

Dedicator Of Cytokinesis 4 (DOCK4) Polyclonal Antibody (Human)

4-PAG184Hu01
  • EUR 247.00
  • EUR 2510.00
  • EUR 625.00
  • EUR 310.00
  • EUR 214.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 4 (DOCK4)

Human Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit

SEG183Hu-10x96wellstestplate 10x96-wells test plate
EUR 4731.5
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Dedicator Of Cytokinesis 3 (DOCK3) in Tissue homogenates and other biological fluids.

Human Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit

SEG183Hu-1x48wellstestplate 1x48-wells test plate
EUR 477.3
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Dedicator Of Cytokinesis 3 (DOCK3) in Tissue homogenates and other biological fluids.

Human Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit

SEG183Hu-1x96wellstestplate 1x96-wells test plate
EUR 639
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Dedicator Of Cytokinesis 3 (DOCK3) in Tissue homogenates and other biological fluids.

Human Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit

SEG183Hu-5x96wellstestplate 5x96-wells test plate
EUR 2575.5
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Dedicator Of Cytokinesis 3 (DOCK3) in Tissue homogenates and other biological fluids.

Human Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit

4-SEG183Hu
  • EUR 4782.00
  • EUR 2526.00
  • EUR 640.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Dedicator Of Cytokinesis 3 (DOCK3) in samples from Tissue homogenates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Human Dedicator Of Cytokinesis 4 (DOCK4) ELISA Kit

SEG184Hu-10x96wellstestplate 10x96-wells test plate
EUR 4731.5
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Dedicator Of Cytokinesis 4 (DOCK4) in Tissue homogenates and other biological fluids.

Human Dedicator Of Cytokinesis 4 (DOCK4) ELISA Kit

SEG184Hu-1x48wellstestplate 1x48-wells test plate
EUR 477.3
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Dedicator Of Cytokinesis 4 (DOCK4) in Tissue homogenates and other biological fluids.

Human Dedicator Of Cytokinesis 4 (DOCK4) ELISA Kit

SEG184Hu-1x96wellstestplate 1x96-wells test plate
EUR 639
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Dedicator Of Cytokinesis 4 (DOCK4) in Tissue homogenates and other biological fluids.

Human Dedicator Of Cytokinesis 4 (DOCK4) ELISA Kit

SEG184Hu-5x96wellstestplate 5x96-wells test plate
EUR 2575.5
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Dedicator Of Cytokinesis 4 (DOCK4) in Tissue homogenates and other biological fluids.

Human Dedicator Of Cytokinesis 4 (DOCK4) ELISA Kit

4-SEG184Hu
  • EUR 4782.00
  • EUR 2526.00
  • EUR 640.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Dedicator Of Cytokinesis 4 (DOCK4) in samples from Tissue homogenates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Human Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit

RD-DOCK3-Hu-48Tests 48 Tests
EUR 521

Human Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit

RD-DOCK3-Hu-96Tests 96 Tests
EUR 723

Human Dedicator Of Cytokinesis 4 (DOCK4) ELISA Kit

RD-DOCK4-Hu-48Tests 48 Tests
EUR 521

Human Dedicator Of Cytokinesis 4 (DOCK4) ELISA Kit

RD-DOCK4-Hu-96Tests 96 Tests
EUR 723

Human Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit

DLR-DOCK3-Hu-48T 48T
EUR 517
Description: A sandwich quantitative ELISA assay kit for detection of Human Dedicator Of Cytokinesis 3 (DOCK3) in samples from tissue homogenates or other biological fluids.

Human Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit

DLR-DOCK3-Hu-96T 96T
EUR 673
Description: A sandwich quantitative ELISA assay kit for detection of Human Dedicator Of Cytokinesis 3 (DOCK3) in samples from tissue homogenates or other biological fluids.

Human Dedicator Of Cytokinesis 4 (DOCK4) ELISA Kit

DLR-DOCK4-Hu-48T 48T
EUR 517
Description: A sandwich quantitative ELISA assay kit for detection of Human Dedicator Of Cytokinesis 4 (DOCK4) in samples from tissue homogenates or other biological fluids.

Human Dedicator Of Cytokinesis 4 (DOCK4) ELISA Kit

DLR-DOCK4-Hu-96T 96T
EUR 673
Description: A sandwich quantitative ELISA assay kit for detection of Human Dedicator Of Cytokinesis 4 (DOCK4) in samples from tissue homogenates or other biological fluids.

Human Dedicator Of Cytokinesis 3 (DOCK3) CLIA Kit

20-abx495120
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Dedicator Of Cytokinesis 4 (DOCK4) CLIA Kit

20-abx495121
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit

20-abx151335
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Dedicator Of Cytokinesis 4 (DOCK4) ELISA Kit

20-abx151336
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit

RDR-DOCK3-Hu-48Tests 48 Tests
EUR 544

Human Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit

RDR-DOCK3-Hu-96Tests 96 Tests
EUR 756

Human Dedicator Of Cytokinesis 4 (DOCK4) ELISA Kit

RDR-DOCK4-Hu-48Tests 48 Tests
EUR 544

Human Dedicator Of Cytokinesis 4 (DOCK4) ELISA Kit

RDR-DOCK4-Hu-96Tests 96 Tests
EUR 756

Human Dedicator Of Cytokinesis 3(DOCK3)ELISA Kit

QY-E04153 96T
EUR 361

ELISA kit for Human Dedicator of cytokinesis protein 4 (DOCK4)

KTE61990-48T 48T
EUR 332
Description: Quantitative sandwich ELISA for measuring Human Dedicator of cytokinesis protein 4 (DOCK4) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Dedicator of cytokinesis protein 4 (DOCK4)

KTE61990-5platesof96wells 5 plates of 96 wells
EUR 2115
Description: Quantitative sandwich ELISA for measuring Human Dedicator of cytokinesis protein 4 (DOCK4) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Dedicator of cytokinesis protein 4 (DOCK4)

KTE61990-96T 96T
EUR 539
Description: Quantitative sandwich ELISA for measuring Human Dedicator of cytokinesis protein 4 (DOCK4) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Dedicator of cytokinesis protein 3 (DOCK3)

KTE61991-48T 48T
EUR 332
Description: Quantitative sandwich ELISA for measuring Human Dedicator of cytokinesis protein 3 (DOCK3) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Dedicator of cytokinesis protein 3 (DOCK3)

KTE61991-5platesof96wells 5 plates of 96 wells
EUR 2115
Description: Quantitative sandwich ELISA for measuring Human Dedicator of cytokinesis protein 3 (DOCK3) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Dedicator of cytokinesis protein 3 (DOCK3)

KTE61991-96T 96T
EUR 539
Description: Quantitative sandwich ELISA for measuring Human Dedicator of cytokinesis protein 3 (DOCK3) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Dedicator Of Cytokinesis 1 (DOCK1) Polyclonal Antibody (Human), APC

4-PAG175Hu01-APC
  • EUR 345.00
  • EUR 3275.00
  • EUR 912.00
  • EUR 440.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 1 (DOCK1). This antibody is labeled with APC.

Dedicator Of Cytokinesis 1 (DOCK1) Polyclonal Antibody (Human), Biotinylated

4-PAG175Hu01-Biotin
  • EUR 311.00
  • EUR 2460.00
  • EUR 727.00
  • EUR 381.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 1 (DOCK1). This antibody is labeled with Biotin.

Dedicator Of Cytokinesis 1 (DOCK1) Polyclonal Antibody (Human), Cy3

4-PAG175Hu01-Cy3
  • EUR 419.00
  • EUR 4325.00
  • EUR 1175.00
  • EUR 545.00
  • EUR 251.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 1 (DOCK1). This antibody is labeled with Cy3.

Dedicator Of Cytokinesis 1 (DOCK1) Polyclonal Antibody (Human), FITC

4-PAG175Hu01-FITC
  • EUR 296.00
  • EUR 2640.00
  • EUR 750.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 1 (DOCK1). This antibody is labeled with FITC.

Dedicator Of Cytokinesis 1 (DOCK1) Polyclonal Antibody (Human), HRP

4-PAG175Hu01-HRP
  • EUR 316.00
  • EUR 2855.00
  • EUR 807.00
  • EUR 398.00
  • EUR 206.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 1 (DOCK1). This antibody is labeled with HRP.

Dedicator Of Cytokinesis 1 (DOCK1) Polyclonal Antibody (Human), PE

4-PAG175Hu01-PE
  • EUR 296.00
  • EUR 2640.00
  • EUR 750.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 1 (DOCK1). This antibody is labeled with PE.

Dedicator Of Cytokinesis 2 (DOCK2) Polyclonal Antibody (Human), APC

4-PAG182Hu01-APC
  • EUR 345.00
  • EUR 3275.00
  • EUR 912.00
  • EUR 440.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 2 (DOCK2). This antibody is labeled with APC.

Dedicator Of Cytokinesis 2 (DOCK2) Polyclonal Antibody (Human), Biotinylated

4-PAG182Hu01-Biotin
  • EUR 311.00
  • EUR 2460.00
  • EUR 727.00
  • EUR 381.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 2 (DOCK2). This antibody is labeled with Biotin.

Dedicator Of Cytokinesis 2 (DOCK2) Polyclonal Antibody (Human), Cy3

4-PAG182Hu01-Cy3
  • EUR 419.00
  • EUR 4325.00
  • EUR 1175.00
  • EUR 545.00
  • EUR 251.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 2 (DOCK2). This antibody is labeled with Cy3.

Dedicator Of Cytokinesis 2 (DOCK2) Polyclonal Antibody (Human), FITC

4-PAG182Hu01-FITC
  • EUR 296.00
  • EUR 2640.00
  • EUR 750.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 2 (DOCK2). This antibody is labeled with FITC.

Dedicator Of Cytokinesis 2 (DOCK2) Polyclonal Antibody (Human), HRP

4-PAG182Hu01-HRP
  • EUR 316.00
  • EUR 2855.00
  • EUR 807.00
  • EUR 398.00
  • EUR 206.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 2 (DOCK2). This antibody is labeled with HRP.

Dedicator Of Cytokinesis 2 (DOCK2) Polyclonal Antibody (Human), PE

4-PAG182Hu01-PE
  • EUR 296.00
  • EUR 2640.00
  • EUR 750.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 2 (DOCK2). This antibody is labeled with PE.

Dedicator Of Cytokinesis 4 (DOCK4) Polyclonal Antibody (Human), APC

4-PAG184Hu01-APC
  • EUR 345.00
  • EUR 3275.00
  • EUR 912.00
  • EUR 440.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 4 (DOCK4). This antibody is labeled with APC.

Dedicator Of Cytokinesis 4 (DOCK4) Polyclonal Antibody (Human), Biotinylated

4-PAG184Hu01-Biotin
  • EUR 311.00
  • EUR 2460.00
  • EUR 727.00
  • EUR 381.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 4 (DOCK4). This antibody is labeled with Biotin.

Dedicator Of Cytokinesis 4 (DOCK4) Polyclonal Antibody (Human), Cy3

4-PAG184Hu01-Cy3
  • EUR 419.00
  • EUR 4325.00
  • EUR 1175.00
  • EUR 545.00
  • EUR 251.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 4 (DOCK4). This antibody is labeled with Cy3.

Dedicator Of Cytokinesis 4 (DOCK4) Polyclonal Antibody (Human), FITC

4-PAG184Hu01-FITC
  • EUR 296.00
  • EUR 2640.00
  • EUR 750.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 4 (DOCK4). This antibody is labeled with FITC.

Dedicator Of Cytokinesis 4 (DOCK4) Polyclonal Antibody (Human), HRP

4-PAG184Hu01-HRP
  • EUR 316.00
  • EUR 2855.00
  • EUR 807.00
  • EUR 398.00
  • EUR 206.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 4 (DOCK4). This antibody is labeled with HRP.

Dedicator Of Cytokinesis 4 (DOCK4) Polyclonal Antibody (Human), PE

4-PAG184Hu01-PE
  • EUR 296.00
  • EUR 2640.00
  • EUR 750.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 4 (DOCK4). This antibody is labeled with PE.

ELISA kit for Human DOCK4 (Dedicator Of Cytokinesis 4)

ELK4741 1 plate of 96 wells
EUR 432
Description: A sandwich ELISA kit for detection of Dedicator Of Cytokinesis 4 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Human DOCK3 (Dedicator Of Cytokinesis 3)

ELK3680 1 plate of 96 wells
EUR 432
Description: A sandwich ELISA kit for detection of Dedicator Of Cytokinesis 3 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Dedicator Of Cytokinesis 1 (DOCK1) Polyclonal Antibody (Human), APC-Cy7

4-PAG175Hu01-APC-Cy7
  • EUR 571.00
  • EUR 6430.00
  • EUR 1705.00
  • EUR 760.00
  • EUR 319.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 1 (DOCK1). This antibody is labeled with APC-Cy7.

Dedicator Of Cytokinesis 2 (DOCK2) Polyclonal Antibody (Human), APC-Cy7

4-PAG182Hu01-APC-Cy7
  • EUR 571.00
  • EUR 6430.00
  • EUR 1705.00
  • EUR 760.00
  • EUR 319.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 2 (DOCK2). This antibody is labeled with APC-Cy7.

Dedicator Of Cytokinesis 4 (DOCK4) Polyclonal Antibody (Human), APC-Cy7

4-PAG184Hu01-APC-Cy7
  • EUR 571.00
  • EUR 6430.00
  • EUR 1705.00
  • EUR 760.00
  • EUR 319.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 4 (DOCK4). This antibody is labeled with APC-Cy7.

Protein Regulator of Cytokinesis 1 (PRC1) Antibody

20-abx114861
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Protein Regulator of Cytokinesis 1 (PRC1) Antibody

abx036162-100ug 100 ug
EUR 391

Protein Regulator of Cytokinesis 1 (PRC1) Antibody

20-abx142167
  • EUR 370.00
  • EUR 606.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 50 ul

Protein Regulator of Cytokinesis 1 (PRC1) Antibody

20-abx006417
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Protein Regulator of Cytokinesis 1 (PRC1) Antibody

abx236748-100ug 100 ug
EUR 481

Protein Regulator of Cytokinesis 1 (PRC1) Antibody

abx236749-100ug 100 ug
EUR 551

Protein regulator of cytokinesis 1 (PRC1) Antibody

20-abx212926
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Protein regulator of cytokinesis 1 (PRC1) Antibody

20-abx325006
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Mouse Protein regulator of cytokinesis 1 (PRC1) ELISA Kit

abx390341-96tests 96 tests
EUR 911

Mouse Protein regulator of cytokinesis 1, Prc1 ELISA KIT

ELI-15432m 96 Tests
EUR 865

Prc1 ELISA Kit| Mouse Protein regulator of cytokinesis 1 ELISA

EF015982 96 Tests
EUR 689

Human Protein regulator of cytokinesis 1 (PRC1) ELISA Kit

abx382447-96tests 96 tests
EUR 911

Human Protein regulator of cytokinesis 1, PRC1 ELISA KIT

ELI-22266h 96 Tests
EUR 824

IL-11 Interleukin-11 Mouse Recombinant Protein

PROTP47873 Regular: 10ug
EUR 317
Description: Interleukin-11 Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids and having a molecular mass of 19.1kDa. ;The Mouse IL-11 is purified by proprietary chromatographic techniques.

Individual Reaction Mix 11

G065-11 200 reactions
EUR 167

Protein regulator of cytokinesis 1 Phospho-Thr481 (PRC1 pT481) Antibody

20-abx325010
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Recombinant Mouse Interleukin-11

7-00934 2µg Ask for price

Recombinant Mouse Interleukin-11

7-00935 10µg Ask for price

Recombinant Mouse Interleukin-11

7-00936 1mg Ask for price

Recombinant Mouse IL-11/ interleukin 11 Protein, Untagged, E.coli-100ug

QP10459-ec-100ug 100ug
EUR 1678

Recombinant Mouse IL-11/ interleukin 11 Protein, Untagged, E.coli-10ug

QP10459-ec-10ug 10ug
EUR 290

Recombinant Mouse IL-11/ interleukin 11 Protein, Untagged, E.coli-250ug

QP10459-ec-250ug 250ug
EUR 2956

Recombinant Mouse IL-11/ interleukin 11 Protein, Untagged, E.coli-2ug

QP10459-ec-2ug 2ug
EUR 154

Recombinant Mouse IL-11/ interleukin 11 Protein, Untagged, E.coli-1mg

QP5472-1mg 1mg
EUR 4952

Recombinant Mouse IL-11/ interleukin 11 Protein, Untagged, E.coli-500ug

QP5472-500ug 500ug
EUR 3038

IL-11 Interleukin-11 Human Recombinant Protein

PROTP20809-1 Regular: 10ug
EUR 317
Description: Interleukin-11 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids and having a molecular mass of 19256.29 Dalton. ;The IL-11 is purified by proprietary chromatographic techniques.

Recombinant Mouse Leptin/Obese Receptor Fc Chimera Protein

OBRFc-11 25 ug
EUR 529

GDF-11 Recombinant Protein

40-209-0005mg 0.005 mg
EUR 259.25
Description: GDF-11 is a myostatin-homologous protein that acts as an inhibitor of nerve tissue growth. GDF-11 has been shown to suppress neurogenesis through a myostatin-like pathway, which involves arrest of progenitor cell-cycle in the G1 phase. Similarities between myostatin and GDF-11, which are 90% identical in their amino acid sequence, suggests that the regulatory mechanisms responsible for maintaining proper tissue size during neural and muscular development might be the same. Recombinant human GDF-11 is a 25.0 kDa disulfide-linked homodimer containing two 109 amino acid polypeptide chains. It is highly homologous to myostatin/GDF-8 sharing 90% amino-acid sequence identity.

GDF-11 Recombinant Protein

40-209-002mg 0.02 mg
EUR 364.25
Description: GDF-11 is a myostatin-homologous protein that acts as an inhibitor of nerve tissue growth. GDF-11 has been shown to suppress neurogenesis through a myostatin-like pathway, which involves arrest of progenitor cell-cycle in the G1 phase. Similarities between myostatin and GDF-11, which are 90% identical in their amino acid sequence, suggests that the regulatory mechanisms responsible for maintaining proper tissue size during neural and muscular development might be the same. Recombinant human GDF-11 is a 25.0 kDa disulfide-linked homodimer containing two 109 amino acid polypeptide chains. It is highly homologous to myostatin/GDF-8 sharing 90% amino-acid sequence identity.

IL-11 Recombinant Protein

40-254-0002mg 0.002 mg
EUR 259.25
Description: IL-11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL-11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury. Recombinant Human IL-11 is a 19.1 kDa protein consisting of 179 amino acid residues.

IL-11 Recombinant Protein

40-254-001mg 0.01 mg
EUR 364.25
Description: IL-11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL-11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury. Recombinant Human IL-11 is a 19.1 kDa protein consisting of 179 amino acid residues.

IL-11 Recombinant Protein

40-437-0002mg 0.002 mg
EUR 259.25
Description: IL-11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL-11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury. Recombinant Murine IL-11 is a 19.1 kDa protein consisting of 179 amino acid residues.

IL-11 Recombinant Protein

40-437-001mg 0.01 mg
EUR 364.25
Description: IL-11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL-11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury. Recombinant Murine IL-11 is a 19.1 kDa protein consisting of 179 amino acid residues.

IL-11 Recombinant Protein

91-005 0.05 mg
EUR 684.5
Description: Interleukin 11 (IL-11) is a thrombopoietic growth factor that directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. IL-11 is a member of a family of human growth factors that includes human growth hormone, granulocyte colony-stimulating factor, and other growth factors.

Kallikrein 11 Recombinant Protein

91-332 0.05 mg
EUR 710.75
Description: Human Kallikrein 11 (KLK11) is a member of tissue kallikrein family which are extracellular serine proteases consisting of 15 members. Two isoforms of KLK11 are differentially expressed. Isoform 1 is predominantly expressed in brain and isoform 2 is preferentially expressed in prostate. Isoform 1 consists of a signal peptide,a short pro peptide and the mature chain.Isoform 2 contains an extra 32 amino acid N terminal to full-length isoform 1.KLK11 is a novel marker for ovarian and prostate cancer carcinomas. KLK11 can be activated by thermolysin and is active against a thioester substrate.

GDF-11 Recombinant Protein

91-641 0.05 mg
EUR 684.5
Description: Growth/differentiation factor 11(GDF-11) is a secreted protein, which belongs to the transforming growth factor beta superfamily. GDF-11 controls anterior-posterior patterning by regulating the expression of Hox genes. The secreted signal acts globally to specify positional identity along the anterior/posterior axis during development. GDF11 has been shown to suppress neurogenesis through a pathway similar to that of myostatin, including stopping the progenitor cell-cycle during G-phase. The similarities between GDF11 and myostatin imply a likelihood that the same regulatory mechanisms are used to control tissue size during both muscular and neural development.

Cadherin-11 Recombinant Protein

91-753 0.05 mg
EUR 542.75
Description: Cadherin-11 is a type II classical cadherin member of the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherins interact with themselves in a homophilic manner in connecting cells, and thus contribute to the sorting of heterogeneous cell types. Cadherin-11 contains five cadherin domains and is mainly expressed in the brain. Mature cadherin proteins consists of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small highly conserved C-terminal cytoplasmic domain. It is shown that Cadherin-11 is a viable molecular target for therapeutic intervention in Glioblastoma multiforme.

Collectin-11 Recombinant Protein

91-761 0.05 mg
EUR 490.25
Description: Collectin-11 is a secreted protein that belongs to the COLEC10/COLEC11 family. Collectin-11 contains one C-type lectin domain and one collagen-like domain. Collectins play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating their recognition and removal. Collectin-11 binds to various sugars including fucose and mannose, but does not bind to glucose, N-acetylglucosamine and N-acetylgalactosamine. It has a higher affinity for fucose compared to mannose. Collectin-11 binds lipopolysaccharides (LPS). It also involved in fundamental development serving as a guidance cue for neural crest cell migration. Defects in Collectin-11 are the cause of 3MC syndrome type 2 (3MC2).

Cadherin-11 Recombinant Protein

91-809 0.05 mg
EUR 490.25
Description: Cadherin-11, also known as OSF-4, Osteoblast cadherin and CDH11, is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherins interact with themselves in a homophilic manner in connecting cells, may thus contribute to the sorting of heterogeneous cell types. Cadherin-11 contains five cadherin domains and is mainly expressed in brain. Mature cadherin proteins consists of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. It is shown that cadherin-11 is a viable molecular target for therapeutic intervention in Glioblastoma multiforme.

IL-11 Recombinant Protein

92-457 0.05 mg
EUR 542.75
Description: Interleukin-11(IL-11) is a secreted protein and belongs to the IL-6 superfamily. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-induced thrombocytopenia, induceacute phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cellproliferation and differentiation and could be use as a therapeutic for osteoporosis. IL-11 stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thickness and strength of long bones. In addition to having lymphopoietic/hematopoietic and osteotrophic properties, it has functions in many other tissues, including the brain, gut, testis and bone.

Recombinant Mouse Interleukin-11/IL-11 (C-Fc)

CJ59-10ug 10ug
EUR 156
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse Interleukin-11/IL-11 (C-Fc)

CJ59-1mg 1mg
EUR 2283
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse Interleukin-11/IL-11 (C-Fc)

CJ59-500ug 500ug
EUR 1613
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse Interleukin-11/IL-11 (C-Fc)

CJ59-50ug 50ug
EUR 369
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Mouse Regulator of G- protein signaling 11, Rgs11 ELISA KIT

ELI-14406m 96 Tests
EUR 865

TREM2 Recombinant Protein

11-127 0.1 mg
EUR 595.25
Description: Triggering receptor expressed on myeloid cells 2 (TREM2) is a cell surface receptor of the immunoglobulin superfamily. The TREM2 is found in various tissue macrophages, such as CNS microglia, bone osteoclasts, alveolar, peritoneal and intestinal macrophages. TREM2 is also present on cultured bone marrow-derived macrophages and monocyte-derived dendritic cells. Some research have identified a rare variant of TREM2 that is a risk factor for Alzheimer disease (AD), which is the most common form of late-onset dementia.The extracellular region of TREM2 contains a single immunoglobulin superfamily domain and binds polyanionic ligands, such as bacterial lipopolysaccharide (LPS) and phospholipids8. Upon ligand binding, TREM2 transmits intracellular signals through an adaptor, DAP12 (also known as TYRO protein tyrosine kinase-binding protein (TYROBP)), which is associated with the transmembrane region of TREM2 and which recruits the protein tyrosine kinase SYK through its cytosolic immunoreceptor tyrosine-based activation motifs (ITAMs). TREM2 is a pro-tumorigenic marker of tumor-infiltrating macrophages in mouse models and human tumors that can be targeted to curb tumor growth and improve the efficacy of checkpoint blockade therapy while remodeling the landscape of tumor-infiltrating macrophages.

CD34 Recombinant Protein

11-132 0.1 mg
EUR 684.5
Description: CD34 molecule is a cluster of differentiation molecule present on certain cells within the human body. It is a cell surface glycoprotein and functions as a cell-cell adhesion factor. It may also mediate the attachment of stem cells to bone marrow extracellular matrix or directly to stromal cells. As a ~ 110 kDa monomeric cell surface antigen, CD34 is highly glycosylated with nine potential N-linked and numerous potential O-linked glycosylation sites in its extracellular domain. The CD34 protein is a member of a family of single-pass transmembrane sialomucin proteins that show expression on early hematopoietic and vascular-associated tissue. CD34 is also an important adhesion molecule and is required for T cells to enter lymph nodes. It is expressed on lymph node endothelia whereas the L-selectin to which it binds is on the T cell. It was indicated that CD34 is a phosphorylation target for activated PKC, and couples to the hematopoietic adapter protein CrkL, which were involved in CD34 signaling pathways. CD34 is abberantly expressed in many kinds of tumors and is implicated in leukemogenesis.

PVRIG Recombinant Protein

11-134 0.1 mg
EUR 595.25
Description: Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.

ZNRF3 Recombinant Protein

11-135 0.1 mg
EUR 595.25
Description: The transmembrane E3 ubiquitin ligase zinc and ring finger 3 (ZNRF3) is a negative feedback regulator of Wnt signalling. ZNRF3 is associated with the Wnt receptor complex, and inhibits Wnt signalling by promoting the turnover of frizzled and LRP6 and acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway.

TREM2 Recombinant Protein

11-138 0.1 mg
EUR 595.25
Description: Triggering receptor expressed on myeloid cells 2 (TREM2) is a cell surface receptor of the immunoglobulin superfamily. The TREM2 is found in various tissue macrophages, such as CNS microglia, bone osteoclasts, alveolar, peritoneal and intestinal macrophages. TREM2 is also present on cultured bone marrow-derived macrophages and monocyte-derived dendritic cells. Some research have identified a rare variant of TREM2 that is a risk factor for Alzheimer disease (AD), which is the most common form of late-onset dementia.The extracellular region of TREM2 contains a single immunoglobulin superfamily domain and binds polyanionic ligands, such as bacterial lipopolysaccharide (LPS) and phospholipids8. Upon ligand binding, TREM2 transmits intracellular signals through an adaptor, DAP12 (also known as TYRO protein tyrosine kinase-binding protein (TYROBP)), which is associated with the transmembrane region of TREM2 and which recruits the protein tyrosine kinase SYK through its cytosolic immunoreceptor tyrosine-based activation motifs (ITAMs). TREM2 is a pro-tumorigenic marker of tumor-infiltrating macrophages in mouse models and human tumors that can be targeted to curb tumor growth and improve the efficacy of checkpoint blockade therapy while remodeling the landscape of tumor-infiltrating macrophages.

TREM2 Recombinant Protein

11-139 0.1 mg
EUR 595.25
Description: Triggering receptor expressed on myeloid cells 2 (TREM2) is a cell surface receptor of the immunoglobulin superfamily. The TREM2 is found in various tissue macrophages, such as CNS microglia, bone osteoclasts, alveolar, peritoneal and intestinal macrophages. TREM2 is also present on cultured bone marrow-derived macrophages and monocyte-derived dendritic cells. Some research have identified a rare variant of TREM2 that is a risk factor for Alzheimer disease (AD), which is the most common form of late-onset dementia.The extracellular region of TREM2 contains a single immunoglobulin superfamily domain and binds polyanionic ligands, such as bacterial lipopolysaccharide (LPS) and phospholipids8. Upon ligand binding, TREM2 transmits intracellular signals through an adaptor, DAP12 (also known as TYRO protein tyrosine kinase-binding protein (TYROBP)), which is associated with the transmembrane region of TREM2 and which recruits the protein tyrosine kinase SYK through its cytosolic immunoreceptor tyrosine-based activation motifs (ITAMs). TREM2 is a pro-tumorigenic marker of tumor-infiltrating macrophages in mouse models and human tumors that can be targeted to curb tumor growth and improve the efficacy of checkpoint blockade therapy while remodeling the landscape of tumor-infiltrating macrophages.

TREM2 Recombinant Protein

11-140 0.1 mg
EUR 595.25
Description: Triggering receptor expressed on myeloid cells 2 (TREM2) is a cell surface receptor of the immunoglobulin superfamily. The TREM2 is found in various tissue macrophages, such as CNS microglia, bone osteoclasts, alveolar, peritoneal and intestinal macrophages. TREM2 is also present on cultured bone marrow-derived macrophages and monocyte-derived dendritic cells. Some research have identified a rare variant of TREM2 that is a risk factor for Alzheimer disease (AD), which is the most common form of late-onset dementia.The extracellular region of TREM2 contains a single immunoglobulin superfamily domain and binds polyanionic ligands, such as bacterial lipopolysaccharide (LPS) and phospholipids8. Upon ligand binding, TREM2 transmits intracellular signals through an adaptor, DAP12 (also known as TYRO protein tyrosine kinase-binding protein (TYROBP)), which is associated with the transmembrane region of TREM2 and which recruits the protein tyrosine kinase SYK through its cytosolic immunoreceptor tyrosine-based activation motifs (ITAMs). TREM2 is a pro-tumorigenic marker of tumor-infiltrating macrophages in mouse models and human tumors that can be targeted to curb tumor growth and improve the efficacy of checkpoint blockade therapy while remodeling the landscape of tumor-infiltrating macrophages.

PVRIG Recombinant Protein

11-148 0.1 mg
EUR 595.25
Description: Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.
Though these therapies didn’t elicit ample results, high-dose administration of intravenous immunoglobulin was profitable. With steroid mini-pulse remedy and the next administration of prednisolone, she recovered efficiently. To the very best of our information, that is the primary report that ICIs and TMP/SMX can induce hypotensive shock accompanied with CRS and DiHS throughout immunosuppressive remedy for an irAE. Importantly, the prophylactic administration of TMP/SMX needs to be carried out cautiously to keep away from extreme drug reactions reminiscent of CRS or DiHS.

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