Leptin and fractalkine: Novel subcutaneous cytokines in burn injury

The liver-derived hormone hepcidin, a member of the defensin household of antimicrobial peptides, performs an vital position in host protection and innate immunity as a result of its broad antibacterial and antiviral properties. Ferritin, an iron storage protein is usually related to iron deficiency, hypoferritinemia, hypoxia, and immune issues, that are all vital issues for systemic an infection in Alzheimer’s illness (AD) and Down’s syndrome (DS) dementia.

Serum and autopsy mind samples have been collected from AD, DS and age-matched management topics. Serum samples have been analyzed with ELISA for ferritin, hepcidin and IL-6. Moreover, autopsy mind sections have been assessed by immunohistochemistry for iron-related and inflammatory proteins. A major enhance in serum hepcidin ranges was present in DS, in comparison with controls and AD topics (p < 0.0001).

Hepcidin protein was seen within the epithelial cells of choroid plexus, meningeal macrophages and within the astrocytes near the endothelium of blood vessels. Hepcidin co-localized with IL-6, indicating its anti-inflammatory properties. We discovered vital correlation between hypoferritinemia and elevated ranges of serum hepcidin in AD and DS. Hepcidin might be transported through macrophages and nearly all of the vesicular hepcidin enters the mind through a compromised blood mind barrier (BBB). Our findings present additional perception into the molecular implications of the altered iron metabolism in acute irritation, and may help in the direction of the event of preventive methods and novel remedies within the combat towards neuroinflammation.

At the moment, only some stories exist on the cytokine launch syndrome (CRS) as one of many extreme immune-related adversarial occasions (irAEs) induced by immune checkpoint inhibitors (ICIs). Notably, it is extremely uncommon that grade Four CRS associated to ICI remedy overlaps with the drug-induced hypersensitivity syndrome (DiHS). A 46-year outdated girl with metastatic kidney most cancers had grade three interstitial pneumonitis induced by 4 cycles of mixture remedy of anti-programmed death-1 and anti-cytotoxic T lymphocyte-Four antibodies after proper cytoreductive nephrectomy.

Prophylactic administration of trimethoprim/sulfamethoxazole (TMP/SMX) was began concomitantly with prednisolone remedy to deal with the interstitial pneumonitis. She developed hypotensive shock when decreasing the dosage of prednisolone, and required intubation and air flow utilizing vasopressors on the intensive care unit.

She subsequently exhibited outstanding leukocytosis and an elevated stage of C-reactive protein, suggesting markedly elevated cytokine ranges. Curiously, facial edema and erythema elevated in affiliation with pyrexia, leukocytosis, liver dysfunction, and renal failure, suggesting that she developed DiHS. She obtained hemodialysis 3 times, a plasma alternate, and anti-interleukin-6 remedy to deal with extreme renal dysfunction, a thrombotic thrombocytopenic purpura-suspected situation, and potential grade Four CRS, respectively.

Mouse Dedicator of cytokinesis protein 8 (Dock8)
1-CSB-YP807451MO1	Cusabio	EUR 586.00 EUR 299.00 EUR 2172.00 EUR 900.00 EUR 1442.00 EUR 382.00	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Mouse Dedicator of cytokinesis protein 8(Dock8),partial expressed in Yeast

Mouse Dedicator of cytokinesis protein 8 (Dock8)
1-CSB-EP807451MO	Cusabio	EUR 505.00 EUR 265.00 EUR 1827.00 EUR 766.00 EUR 1218.00 EUR 335.00	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Mouse Dedicator of cytokinesis protein 8(Dock8),partial expressed in E.coli

Mouse Dedicator of cytokinesis protein 8 (Dock8)
1-CSB-EP807451MO1	Cusabio	EUR 505.00 EUR 265.00 EUR 1827.00 EUR 766.00 EUR 1218.00 EUR 335.00	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Mouse Dedicator of cytokinesis protein 8(Dock8),partial expressed in E.coli

Dedicator of Cytokinesis 2 (DOCK2) Antibody
20-abx126888	Abbexa	EUR 411.00 EUR 592.00	100 ul 200 ul

Dedicator of Cytokinesis 2 (DOCK2) Antibody
20-abx129016	Abbexa	EUR 425.00 EUR 133.00 EUR 1205.00 EUR 578.00 EUR 328.00	100 ug 10 ug 1 mg 200 ug 50 ug

Dedicator of Cytokinesis 4 (DOCK4) Antibody
20-abx129252	Abbexa	EUR 425.00 EUR 133.00 EUR 1205.00 EUR 578.00 EUR 328.00	100 ug 10 ug 1 mg 200 ug 50 ug

Dedicator of Cytokinesis 1 (DOCK1) Antibody
20-abx112009	Abbexa	EUR 732.00 EUR 398.00	150 ul 50 ul

Dedicator of Cytokinesis 2 (DOCK2) Antibody
20-abx112010	Abbexa	EUR 732.00 EUR 398.00	150 ul 50 ul

Dedicator of Cytokinesis 3 (DOCK3) Antibody
20-abx112011	Abbexa	EUR 732.00 EUR 398.00	150 ul 50 ul

Dedicator of Cytokinesis 3 (DOCK3) Antibody
20-abx313603	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Dedicator of Cytokinesis 1 (DOCK1) Antibody
20-abx102732	Abbexa	EUR 425.00 EUR 133.00 EUR 1205.00 EUR 578.00 EUR 328.00	100 ug 10 ug 1 mg 200 ug 50 ug

Dedicator of Cytokinesis 2 (DOCK2) Antibody
20-abx149900	Abbexa	EUR 425.00 EUR 342.00	100 ug 50 ug

Dedicator of Cytokinesis 1 (DOCK1) Antibody
abx147652-100ug	Abbexa	100 ug	EUR 439

Dedicator of Cytokinesis 1 (DOCK1) Antibody
20-abx014419	Abbexa	EUR 314.00 EUR 98.00 EUR 398.00 EUR 495.00	100 ug 10 ug 200 ug 300 µg

Dedicator of Cytokinesis 1 (DOCK1) Antibody
abx431929-200ul	Abbexa	200 ul	EUR 384

Dedicator Of Cytokinesis 1 (DOCK1) Antibody
20-abx211608	Abbexa	EUR 411.00 EUR 300.00	100 ul 50 ul

Dedicator Of Cytokinesis 3 (DOCK3) Antibody
20-abx176110	Abbexa	EUR 1205.00 EUR 578.00	1 mg 200 ug

Dedicator Of Cytokinesis 3 (DOCK3) Antibody
20-abx172052	Abbexa	EUR 857.00 EUR 439.00	1 mg 200 ug

Dedicator Of Cytokinesis 4 (DOCK4) Antibody
20-abx172053	Abbexa	EUR 857.00 EUR 439.00	1 mg 200 ug

Dedicator Of Cytokinesis 1 (DOCK1) Antibody
abx330938-100ul	Abbexa	100 ul	EUR 425

Dedicator Of Cytokinesis 2 (DOCK2) Antibody
20-abx326569	Abbexa	EUR 314.00 EUR 244.00	100 ug 50 ug

Dedicator Of Cytokinesis 1 (DOCK1) Antibody
20-abx325559	Abbexa	EUR 314.00 EUR 244.00	100 ug 50 ug

Dedicator Of Cytokinesis 1 (DOCK1) Antibody
20-abx333995	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Human Dedicator of cytokinesis protein 8 (DOCK8)
1-CSB-YP836734HU	Cusabio	EUR 504.00 EUR 265.00 EUR 1832.00 EUR 763.00 EUR 1216.00 EUR 334.00	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Human Dedicator of cytokinesis protein 8(DOCK8),partial expressed in Yeast

Human Dedicator of cytokinesis protein 8 (DOCK8)
1-CSB-YP836734HUb0	Cusabio	EUR 504.00 EUR 265.00 EUR 1832.00 EUR 763.00 EUR 1216.00 EUR 334.00	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Human Dedicator of cytokinesis protein 8(DOCK8),partial expressed in Yeast

Dedicator of Cytokinesis Protein 5 (DOCK5) Antibody
abx122686-100ug	Abbexa	100 ug	EUR 391

Dedicator of Cytokinesis Protein 5 (DOCK5) Antibody
20-abx311377	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Human Dedicator Of Cytokinesis 3 (DOCK3) Protein
20-abx653130	Abbexa	EUR 578.00 EUR 258.00 EUR 1720.00 EUR 690.00 EUR 425.00	100 ug 10 ug 1 mg 200 ug 50 ug

Human Dedicator Of Cytokinesis 1 (DOCK1) Protein
20-abx066282	Abbexa	EUR 648.00 EUR 272.00 EUR 1998.00 EUR 773.00 EUR 467.00	100 ug 10 ug 1 mg 200 ug 50 ug

Dedicator of Cytokinesis Protein 10 (DOCK10) Antibody
abx145342-100ug	Abbexa	100 ug	EUR 391

Human Dedicator Of Cytokinesis 2 (DOCK2) Protein
20-abx166509	Abbexa	EUR 648.00 EUR 272.00 EUR 1943.00 EUR 759.00 EUR 467.00	100 ug 10 ug 1 mg 200 ug 50 ug

Human Dedicator Of Cytokinesis 4 (DOCK4) Protein
20-abx168105	Abbexa	EUR 648.00 EUR 272.00 EUR 1998.00 EUR 773.00 EUR 467.00	100 ug 10 ug 1 mg 200 ug 50 ug

Dedicator of Cytokinesis Protein 10 (DOCK10) Antibody
20-abx301562	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Mouse Dedicator of cytokinesis protein 9, Dock9 ELISA KIT
ELI-26224m	Lifescience Market	96 Tests	EUR 865

Mouse Dedicator of cytokinesis protein 4, Dock4 ELISA KIT
ELI-26847m	Lifescience Market	96 Tests	EUR 865

Mouse Dedicator of cytokinesis protein 5, Dock5 ELISA KIT
ELI-26848m	Lifescience Market	96 Tests	EUR 865

Mouse Dedicator of cytokinesis protein 1, Dock1 ELISA KIT
ELI-47076m	Lifescience Market	96 Tests	EUR 865

Mouse Dedicator of cytokinesis protein 2, Dock2 ELISA KIT
ELI-47799m	Lifescience Market	96 Tests	EUR 865

Mouse Dedicator of cytokinesis protein 7, Dock7 ELISA KIT
ELI-32144m	Lifescience Market	96 Tests	EUR 865

Mouse Dedicator of cytokinesis protein 6, Dock6 ELISA KIT
ELI-32830m	Lifescience Market	96 Tests	EUR 865

Mouse Dedicator of cytokinesis protein 10, Dock10 ELISA KIT
ELI-31732m	Lifescience Market	96 Tests	EUR 865

Mouse Dedicator of cytokinesis protein 3, Dock3 ELISA KIT
ELI-09219m	Lifescience Market	96 Tests	EUR 865

Mouse Dedicator of cytokinesis protein 8, Dock8 ELISA KIT
ELI-09684m	Lifescience Market	96 Tests	EUR 865

Dedicator of Cytokinesis 3 (DOCK3) Antibody (HRP)
20-abx313604	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Dedicator of Cytokinesis 3 (DOCK3) Antibody (FITC)
20-abx313605	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Dedicator of Cytokinesis 3 (DOCK3) Antibody (Biotin)
20-abx313606	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Dedicator Of Cytokinesis 1 (DOCK1) Antibody (HRP)
20-abx335295	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Dedicator Of Cytokinesis 1 (DOCK1) Antibody (FITC)
20-abx335296	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Dedicator Of Cytokinesis 1 (DOCK1) Antibody (Biotin)
20-abx335297	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Human Dedicator Of Cytokinesis Protein 6 (DOCK6) ELISA Kit
abx386963-96tests	Abbexa	96 tests	EUR 911

Human Dedicator Of Cytokinesis Protein 7 (DOCK7) ELISA Kit
abx386964-96tests	Abbexa	96 tests	EUR 911

Human Dedicator Of Cytokinesis Protein 8 (DOCK8) ELISA Kit
abx386965-96tests	Abbexa	96 tests	EUR 911

Human Dedicator Of Cytokinesis Protein 9 (DOCK9) ELISA Kit
abx386966-96tests	Abbexa	96 tests	EUR 911

Human Dedicator Of Cytokinesis Protein 1 (DOCK1) ELISA Kit
abx259546-96tests	Abbexa	96 tests	EUR 911

Human Dedicator of cytokinesis protein 6, DOCK6 ELISA KIT
ELI-26222h	Lifescience Market	96 Tests	EUR 824

Human Dedicator of cytokinesis protein 9, DOCK9 ELISA KIT
ELI-26223h	Lifescience Market	96 Tests	EUR 824

Human Dedicator of cytokinesis protein 2, DOCK2 ELISA KIT
ELI-46901h	Lifescience Market	96 Tests	EUR 824

Human Dedicator of cytokinesis protein 10, DOCK10 ELISA KIT
ELI-47075h	Lifescience Market	96 Tests	EUR 824

Human Dedicator of cytokinesis protein 3, DOCK3 ELISA KIT
ELI-32143h	Lifescience Market	96 Tests	EUR 824

Human Dedicator of cytokinesis protein 7, DOCK7 ELISA KIT
ELI-31733h	Lifescience Market	96 Tests	EUR 824

Human Dedicator of cytokinesis protein 4, DOCK4 ELISA KIT
ELI-08843h	Lifescience Market	96 Tests	EUR 824

Human Dedicator of cytokinesis protein 1, DOCK1 ELISA KIT
ELI-09218h	Lifescience Market	96 Tests	EUR 824

Human Dedicator of cytokinesis protein 5, DOCK5 ELISA KIT
ELI-09220h	Lifescience Market	96 Tests	EUR 824

Human Dedicator of cytokinesis protein 8, DOCK8 ELISA KIT
ELI-09221h	Lifescience Market	96 Tests	EUR 824

Dedicator Of Cytokinesis 1 (DOCK1) Polyclonal Antibody (Human)
4-PAG175Hu01	Cloud-Clone	EUR 247.00 EUR 2510.00 EUR 625.00 EUR 310.00 EUR 214.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 1 (DOCK1)

Dedicator Of Cytokinesis 2 (DOCK2) Polyclonal Antibody (Human)
4-PAG182Hu01	Cloud-Clone	EUR 247.00 EUR 2510.00 EUR 625.00 EUR 310.00 EUR 214.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 2 (DOCK2)

Dedicator Of Cytokinesis 4 (DOCK4) Polyclonal Antibody (Human)
4-PAG184Hu01	Cloud-Clone	EUR 247.00 EUR 2510.00 EUR 625.00 EUR 310.00 EUR 214.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 4 (DOCK4)

Human Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit
SEG183Hu-10x96wellstestplate	Cloud-Clone	10x96-wells test plate	EUR 4731.5
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Dedicator Of Cytokinesis 3 (DOCK3) in Tissue homogenates and other biological fluids.

Human Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit
SEG183Hu-1x48wellstestplate	Cloud-Clone	1x48-wells test plate	EUR 477.3
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Dedicator Of Cytokinesis 3 (DOCK3) in Tissue homogenates and other biological fluids.

Human Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit
SEG183Hu-1x96wellstestplate	Cloud-Clone	1x96-wells test plate	EUR 639
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Dedicator Of Cytokinesis 3 (DOCK3) in Tissue homogenates and other biological fluids.

Human Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit
SEG183Hu-5x96wellstestplate	Cloud-Clone	5x96-wells test plate	EUR 2575.5
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Dedicator Of Cytokinesis 3 (DOCK3) in Tissue homogenates and other biological fluids.

Human Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit
4-SEG183Hu	Cloud-Clone	EUR 4782.00 EUR 2526.00 EUR 640.00	10 plates of 96 wells 5 plates of 96 wells 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Dedicator Of Cytokinesis 3 (DOCK3) in samples from Tissue homogenates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Human Dedicator Of Cytokinesis 4 (DOCK4) ELISA Kit
SEG184Hu-10x96wellstestplate	Cloud-Clone	10x96-wells test plate	EUR 4731.5
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Dedicator Of Cytokinesis 4 (DOCK4) in Tissue homogenates and other biological fluids.

Human Dedicator Of Cytokinesis 4 (DOCK4) ELISA Kit
SEG184Hu-1x48wellstestplate	Cloud-Clone	1x48-wells test plate	EUR 477.3
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Dedicator Of Cytokinesis 4 (DOCK4) in Tissue homogenates and other biological fluids.

Human Dedicator Of Cytokinesis 4 (DOCK4) ELISA Kit
SEG184Hu-1x96wellstestplate	Cloud-Clone	1x96-wells test plate	EUR 639
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Dedicator Of Cytokinesis 4 (DOCK4) in Tissue homogenates and other biological fluids.

Human Dedicator Of Cytokinesis 4 (DOCK4) ELISA Kit
SEG184Hu-5x96wellstestplate	Cloud-Clone	5x96-wells test plate	EUR 2575.5
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Dedicator Of Cytokinesis 4 (DOCK4) in Tissue homogenates and other biological fluids.

Human Dedicator Of Cytokinesis 4 (DOCK4) ELISA Kit
4-SEG184Hu	Cloud-Clone	EUR 4782.00 EUR 2526.00 EUR 640.00	10 plates of 96 wells 5 plates of 96 wells 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Dedicator Of Cytokinesis 4 (DOCK4) in samples from Tissue homogenates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Human Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit
RD-DOCK3-Hu-48Tests	Reddot Biotech	48 Tests	EUR 521

Human Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit
RD-DOCK3-Hu-96Tests	Reddot Biotech	96 Tests	EUR 723

Human Dedicator Of Cytokinesis 4 (DOCK4) ELISA Kit
RD-DOCK4-Hu-48Tests	Reddot Biotech	48 Tests	EUR 521

Human Dedicator Of Cytokinesis 4 (DOCK4) ELISA Kit
RD-DOCK4-Hu-96Tests	Reddot Biotech	96 Tests	EUR 723

Human Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit
DLR-DOCK3-Hu-48T	DL Develop	48T	EUR 517
Description: A sandwich quantitative ELISA assay kit for detection of Human Dedicator Of Cytokinesis 3 (DOCK3) in samples from tissue homogenates or other biological fluids.

Human Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit
DLR-DOCK3-Hu-96T	DL Develop	96T	EUR 673
Description: A sandwich quantitative ELISA assay kit for detection of Human Dedicator Of Cytokinesis 3 (DOCK3) in samples from tissue homogenates or other biological fluids.

Human Dedicator Of Cytokinesis 4 (DOCK4) ELISA Kit
DLR-DOCK4-Hu-48T	DL Develop	48T	EUR 517
Description: A sandwich quantitative ELISA assay kit for detection of Human Dedicator Of Cytokinesis 4 (DOCK4) in samples from tissue homogenates or other biological fluids.

Human Dedicator Of Cytokinesis 4 (DOCK4) ELISA Kit
DLR-DOCK4-Hu-96T	DL Develop	96T	EUR 673
Description: A sandwich quantitative ELISA assay kit for detection of Human Dedicator Of Cytokinesis 4 (DOCK4) in samples from tissue homogenates or other biological fluids.

Human Dedicator Of Cytokinesis 3 (DOCK3) CLIA Kit
20-abx495120	Abbexa	EUR 7973.00 EUR 4246.00 EUR 981.00	10 × 96 tests 5 × 96 tests 96 tests

Human Dedicator Of Cytokinesis 4 (DOCK4) CLIA Kit
20-abx495121	Abbexa	EUR 7973.00 EUR 4246.00 EUR 981.00	10 × 96 tests 5 × 96 tests 96 tests

Human Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit
20-abx151335	Abbexa	EUR 7378.00 EUR 3933.00 EUR 911.00	10 × 96 tests 5 × 96 tests 96 tests

Human Dedicator Of Cytokinesis 4 (DOCK4) ELISA Kit
20-abx151336	Abbexa	EUR 7378.00 EUR 3933.00 EUR 911.00	10 × 96 tests 5 × 96 tests 96 tests

Human Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit
RDR-DOCK3-Hu-48Tests	Reddot Biotech	48 Tests	EUR 544

Human Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit
RDR-DOCK3-Hu-96Tests	Reddot Biotech	96 Tests	EUR 756

Human Dedicator Of Cytokinesis 4 (DOCK4) ELISA Kit
RDR-DOCK4-Hu-48Tests	Reddot Biotech	48 Tests	EUR 544

Human Dedicator Of Cytokinesis 4 (DOCK4) ELISA Kit
RDR-DOCK4-Hu-96Tests	Reddot Biotech	96 Tests	EUR 756

Human Dedicator Of Cytokinesis 3(DOCK3)ELISA Kit
QY-E04153	Qayee Biotechnology	96T	EUR 361

ELISA kit for Human Dedicator of cytokinesis protein 4 (DOCK4)
KTE61990-48T	Abbkine	48T	EUR 332
Description: Quantitative sandwich ELISA for measuring Human Dedicator of cytokinesis protein 4 (DOCK4) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Dedicator of cytokinesis protein 4 (DOCK4)
KTE61990-5platesof96wells	Abbkine	5 plates of 96 wells	EUR 2115
Description: Quantitative sandwich ELISA for measuring Human Dedicator of cytokinesis protein 4 (DOCK4) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Dedicator of cytokinesis protein 4 (DOCK4)
KTE61990-96T	Abbkine	96T	EUR 539
Description: Quantitative sandwich ELISA for measuring Human Dedicator of cytokinesis protein 4 (DOCK4) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Dedicator of cytokinesis protein 3 (DOCK3)
KTE61991-48T	Abbkine	48T	EUR 332
Description: Quantitative sandwich ELISA for measuring Human Dedicator of cytokinesis protein 3 (DOCK3) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Dedicator of cytokinesis protein 3 (DOCK3)
KTE61991-5platesof96wells	Abbkine	5 plates of 96 wells	EUR 2115
Description: Quantitative sandwich ELISA for measuring Human Dedicator of cytokinesis protein 3 (DOCK3) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Dedicator of cytokinesis protein 3 (DOCK3)
KTE61991-96T	Abbkine	96T	EUR 539
Description: Quantitative sandwich ELISA for measuring Human Dedicator of cytokinesis protein 3 (DOCK3) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Dedicator Of Cytokinesis 1 (DOCK1) Polyclonal Antibody (Human), APC
4-PAG175Hu01-APC	Cloud-Clone	EUR 345.00 EUR 3275.00 EUR 912.00 EUR 440.00 EUR 219.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 1 (DOCK1). This antibody is labeled with APC.

Dedicator Of Cytokinesis 1 (DOCK1) Polyclonal Antibody (Human), Biotinylated
4-PAG175Hu01-Biotin	Cloud-Clone	EUR 311.00 EUR 2460.00 EUR 727.00 EUR 381.00 EUR 219.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 1 (DOCK1). This antibody is labeled with Biotin.

Dedicator Of Cytokinesis 1 (DOCK1) Polyclonal Antibody (Human), Cy3
4-PAG175Hu01-Cy3	Cloud-Clone	EUR 419.00 EUR 4325.00 EUR 1175.00 EUR 545.00 EUR 251.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 1 (DOCK1). This antibody is labeled with Cy3.

Dedicator Of Cytokinesis 1 (DOCK1) Polyclonal Antibody (Human), FITC
4-PAG175Hu01-FITC	Cloud-Clone	EUR 296.00 EUR 2640.00 EUR 750.00 EUR 372.00 EUR 195.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 1 (DOCK1). This antibody is labeled with FITC.

Dedicator Of Cytokinesis 1 (DOCK1) Polyclonal Antibody (Human), HRP
4-PAG175Hu01-HRP	Cloud-Clone	EUR 316.00 EUR 2855.00 EUR 807.00 EUR 398.00 EUR 206.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 1 (DOCK1). This antibody is labeled with HRP.

Dedicator Of Cytokinesis 1 (DOCK1) Polyclonal Antibody (Human), PE
4-PAG175Hu01-PE	Cloud-Clone	EUR 296.00 EUR 2640.00 EUR 750.00 EUR 372.00 EUR 195.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 1 (DOCK1). This antibody is labeled with PE.

Dedicator Of Cytokinesis 2 (DOCK2) Polyclonal Antibody (Human), APC
4-PAG182Hu01-APC	Cloud-Clone	EUR 345.00 EUR 3275.00 EUR 912.00 EUR 440.00 EUR 219.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 2 (DOCK2). This antibody is labeled with APC.

Dedicator Of Cytokinesis 2 (DOCK2) Polyclonal Antibody (Human), Biotinylated
4-PAG182Hu01-Biotin	Cloud-Clone	EUR 311.00 EUR 2460.00 EUR 727.00 EUR 381.00 EUR 219.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 2 (DOCK2). This antibody is labeled with Biotin.

Dedicator Of Cytokinesis 2 (DOCK2) Polyclonal Antibody (Human), Cy3
4-PAG182Hu01-Cy3	Cloud-Clone	EUR 419.00 EUR 4325.00 EUR 1175.00 EUR 545.00 EUR 251.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 2 (DOCK2). This antibody is labeled with Cy3.

Dedicator Of Cytokinesis 2 (DOCK2) Polyclonal Antibody (Human), FITC
4-PAG182Hu01-FITC	Cloud-Clone	EUR 296.00 EUR 2640.00 EUR 750.00 EUR 372.00 EUR 195.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 2 (DOCK2). This antibody is labeled with FITC.

Dedicator Of Cytokinesis 2 (DOCK2) Polyclonal Antibody (Human), HRP
4-PAG182Hu01-HRP	Cloud-Clone	EUR 316.00 EUR 2855.00 EUR 807.00 EUR 398.00 EUR 206.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 2 (DOCK2). This antibody is labeled with HRP.

Dedicator Of Cytokinesis 2 (DOCK2) Polyclonal Antibody (Human), PE
4-PAG182Hu01-PE	Cloud-Clone	EUR 296.00 EUR 2640.00 EUR 750.00 EUR 372.00 EUR 195.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 2 (DOCK2). This antibody is labeled with PE.

Dedicator Of Cytokinesis 4 (DOCK4) Polyclonal Antibody (Human), APC
4-PAG184Hu01-APC	Cloud-Clone	EUR 345.00 EUR 3275.00 EUR 912.00 EUR 440.00 EUR 219.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 4 (DOCK4). This antibody is labeled with APC.

Dedicator Of Cytokinesis 4 (DOCK4) Polyclonal Antibody (Human), Biotinylated
4-PAG184Hu01-Biotin	Cloud-Clone	EUR 311.00 EUR 2460.00 EUR 727.00 EUR 381.00 EUR 219.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 4 (DOCK4). This antibody is labeled with Biotin.

Dedicator Of Cytokinesis 4 (DOCK4) Polyclonal Antibody (Human), Cy3
4-PAG184Hu01-Cy3	Cloud-Clone	EUR 419.00 EUR 4325.00 EUR 1175.00 EUR 545.00 EUR 251.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 4 (DOCK4). This antibody is labeled with Cy3.

Dedicator Of Cytokinesis 4 (DOCK4) Polyclonal Antibody (Human), FITC
4-PAG184Hu01-FITC	Cloud-Clone	EUR 296.00 EUR 2640.00 EUR 750.00 EUR 372.00 EUR 195.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 4 (DOCK4). This antibody is labeled with FITC.

Dedicator Of Cytokinesis 4 (DOCK4) Polyclonal Antibody (Human), HRP
4-PAG184Hu01-HRP	Cloud-Clone	EUR 316.00 EUR 2855.00 EUR 807.00 EUR 398.00 EUR 206.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 4 (DOCK4). This antibody is labeled with HRP.

Dedicator Of Cytokinesis 4 (DOCK4) Polyclonal Antibody (Human), PE
4-PAG184Hu01-PE	Cloud-Clone	EUR 296.00 EUR 2640.00 EUR 750.00 EUR 372.00 EUR 195.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 4 (DOCK4). This antibody is labeled with PE.

ELISA kit for Human DOCK4 (Dedicator Of Cytokinesis 4)
ELK4741	ELK Biotech	1 plate of 96 wells	EUR 432
Description: A sandwich ELISA kit for detection of Dedicator Of Cytokinesis 4 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Human DOCK3 (Dedicator Of Cytokinesis 3)
ELK3680	ELK Biotech	1 plate of 96 wells	EUR 432
Description: A sandwich ELISA kit for detection of Dedicator Of Cytokinesis 3 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Dedicator Of Cytokinesis 1 (DOCK1) Polyclonal Antibody (Human), APC-Cy7
4-PAG175Hu01-APC-Cy7	Cloud-Clone	EUR 571.00 EUR 6430.00 EUR 1705.00 EUR 760.00 EUR 319.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 1 (DOCK1). This antibody is labeled with APC-Cy7.

Dedicator Of Cytokinesis 2 (DOCK2) Polyclonal Antibody (Human), APC-Cy7
4-PAG182Hu01-APC-Cy7	Cloud-Clone	EUR 571.00 EUR 6430.00 EUR 1705.00 EUR 760.00 EUR 319.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 2 (DOCK2). This antibody is labeled with APC-Cy7.

Dedicator Of Cytokinesis 4 (DOCK4) Polyclonal Antibody (Human), APC-Cy7
4-PAG184Hu01-APC-Cy7	Cloud-Clone	EUR 571.00 EUR 6430.00 EUR 1705.00 EUR 760.00 EUR 319.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 4 (DOCK4). This antibody is labeled with APC-Cy7.

Protein Regulator of Cytokinesis 1 (PRC1) Antibody
20-abx114861	Abbexa	EUR 732.00 EUR 398.00	150 ul 50 ul

Protein Regulator of Cytokinesis 1 (PRC1) Antibody
abx036162-100ug	Abbexa	100 ug	EUR 391

Protein Regulator of Cytokinesis 1 (PRC1) Antibody
20-abx142167	Abbexa	EUR 370.00 EUR 606.00 EUR 314.00	100 ul 200 ul 50 ul

Protein Regulator of Cytokinesis 1 (PRC1) Antibody
20-abx006417	Abbexa	EUR 411.00 EUR 592.00 EUR 182.00 EUR 314.00	100 ul 200 ul 20 ul 50 ul

Protein Regulator of Cytokinesis 1 (PRC1) Antibody
abx236748-100ug	Abbexa	100 ug	EUR 481

Protein Regulator of Cytokinesis 1 (PRC1) Antibody
abx236749-100ug	Abbexa	100 ug	EUR 551

Protein regulator of cytokinesis 1 (PRC1) Antibody
20-abx212926	Abbexa	EUR 411.00 EUR 300.00	100 ul 50 ul

Protein regulator of cytokinesis 1 (PRC1) Antibody
20-abx325006	Abbexa	EUR 314.00 EUR 244.00	100 ug 50 ug

Mouse Protein regulator of cytokinesis 1 (PRC1) ELISA Kit
abx390341-96tests	Abbexa	96 tests	EUR 911

Mouse Protein regulator of cytokinesis 1, Prc1 ELISA KIT
ELI-15432m	Lifescience Market	96 Tests	EUR 865

Prc1 ELISA Kit| Mouse Protein regulator of cytokinesis 1 ELISA
EF015982	Lifescience Market	96 Tests	EUR 689

Human Protein regulator of cytokinesis 1 (PRC1) ELISA Kit
abx382447-96tests	Abbexa	96 tests	EUR 911

Human Protein regulator of cytokinesis 1, PRC1 ELISA KIT
ELI-22266h	Lifescience Market	96 Tests	EUR 824

IL-11 Interleukin-11 Mouse Recombinant Protein
PROTP47873	BosterBio	Regular: 10ug	EUR 317
Description: Interleukin-11 Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids and having a molecular mass of 19.1kDa. ;The Mouse IL-11 is purified by proprietary chromatographic techniques.

Individual Reaction Mix 11
G065-11	ABM	200 reactions	EUR 167

Protein regulator of cytokinesis 1 Phospho-Thr481 (PRC1 pT481) Antibody
20-abx325010	Abbexa	EUR 314.00 EUR 244.00	100 ug 50 ug

Recombinant Mouse Interleukin-11
7-00934	CHI Scientific	2µg	Ask for price

Recombinant Mouse Interleukin-11
7-00935	CHI Scientific	10µg	Ask for price

Recombinant Mouse Interleukin-11
7-00936	CHI Scientific	1mg	Ask for price

Recombinant Mouse IL-11/ interleukin 11 Protein, Untagged, E.coli-100ug
QP10459-ec-100ug	EnQuireBio	100ug	EUR 1678

Recombinant Mouse IL-11/ interleukin 11 Protein, Untagged, E.coli-10ug
QP10459-ec-10ug	EnQuireBio	10ug	EUR 290

Recombinant Mouse IL-11/ interleukin 11 Protein, Untagged, E.coli-250ug
QP10459-ec-250ug	EnQuireBio	250ug	EUR 2956

Recombinant Mouse IL-11/ interleukin 11 Protein, Untagged, E.coli-2ug
QP10459-ec-2ug	EnQuireBio	2ug	EUR 154

Recombinant Mouse IL-11/ interleukin 11 Protein, Untagged, E.coli-1mg
QP5472-1mg	EnQuireBio	1mg	EUR 4952

Recombinant Mouse IL-11/ interleukin 11 Protein, Untagged, E.coli-500ug
QP5472-500ug	EnQuireBio	500ug	EUR 3038

IL-11 Interleukin-11 Human Recombinant Protein
PROTP20809-1	BosterBio	Regular: 10ug	EUR 317
Description: Interleukin-11 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids and having a molecular mass of 19256.29 Dalton. ;The IL-11 is purified by proprietary chromatographic techniques.

Recombinant Mouse Leptin/Obese Receptor Fc Chimera Protein
OBRFc-11	Alpha Diagnostics	25 ug	EUR 529

GDF-11 Recombinant Protein
40-209-0005mg	ProSci	0.005 mg	EUR 259.25
Description: GDF-11 is a myostatin-homologous protein that acts as an inhibitor of nerve tissue growth. GDF-11 has been shown to suppress neurogenesis through a myostatin-like pathway, which involves arrest of progenitor cell-cycle in the G1 phase. Similarities between myostatin and GDF-11, which are 90% identical in their amino acid sequence, suggests that the regulatory mechanisms responsible for maintaining proper tissue size during neural and muscular development might be the same. Recombinant human GDF-11 is a 25.0 kDa disulfide-linked homodimer containing two 109 amino acid polypeptide chains. It is highly homologous to myostatin/GDF-8 sharing 90% amino-acid sequence identity.

GDF-11 Recombinant Protein
40-209-002mg	ProSci	0.02 mg	EUR 364.25
Description: GDF-11 is a myostatin-homologous protein that acts as an inhibitor of nerve tissue growth. GDF-11 has been shown to suppress neurogenesis through a myostatin-like pathway, which involves arrest of progenitor cell-cycle in the G1 phase. Similarities between myostatin and GDF-11, which are 90% identical in their amino acid sequence, suggests that the regulatory mechanisms responsible for maintaining proper tissue size during neural and muscular development might be the same. Recombinant human GDF-11 is a 25.0 kDa disulfide-linked homodimer containing two 109 amino acid polypeptide chains. It is highly homologous to myostatin/GDF-8 sharing 90% amino-acid sequence identity.

IL-11 Recombinant Protein
40-254-0002mg	ProSci	0.002 mg	EUR 259.25
Description: IL-11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL-11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury. Recombinant Human IL-11 is a 19.1 kDa protein consisting of 179 amino acid residues.

IL-11 Recombinant Protein
40-254-001mg	ProSci	0.01 mg	EUR 364.25
Description: IL-11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL-11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury. Recombinant Human IL-11 is a 19.1 kDa protein consisting of 179 amino acid residues.

IL-11 Recombinant Protein
40-437-0002mg	ProSci	0.002 mg	EUR 259.25
Description: IL-11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL-11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury. Recombinant Murine IL-11 is a 19.1 kDa protein consisting of 179 amino acid residues.

IL-11 Recombinant Protein
40-437-001mg	ProSci	0.01 mg	EUR 364.25
Description: IL-11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL-11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury. Recombinant Murine IL-11 is a 19.1 kDa protein consisting of 179 amino acid residues.

IL-11 Recombinant Protein
91-005	ProSci	0.05 mg	EUR 684.5
Description: Interleukin 11 (IL-11) is a thrombopoietic growth factor that directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. IL-11 is a member of a family of human growth factors that includes human growth hormone, granulocyte colony-stimulating factor, and other growth factors.

Kallikrein 11 Recombinant Protein
91-332	ProSci	0.05 mg	EUR 710.75
Description: Human Kallikrein 11 (KLK11) is a member of tissue kallikrein family which are extracellular serine proteases consisting of 15 members. Two isoforms of KLK11 are differentially expressed. Isoform 1 is predominantly expressed in brain and isoform 2 is preferentially expressed in prostate. Isoform 1 consists of a signal peptide,a short pro peptide and the mature chain.Isoform 2 contains an extra 32 amino acid N terminal to full-length isoform 1.KLK11 is a novel marker for ovarian and prostate cancer carcinomas. KLK11 can be activated by thermolysin and is active against a thioester substrate.

GDF-11 Recombinant Protein
91-641	ProSci	0.05 mg	EUR 684.5
Description: Growth/differentiation factor 11(GDF-11) is a secreted protein, which belongs to the transforming growth factor beta superfamily. GDF-11 controls anterior-posterior patterning by regulating the expression of Hox genes. The secreted signal acts globally to specify positional identity along the anterior/posterior axis during development. GDF11 has been shown to suppress neurogenesis through a pathway similar to that of myostatin, including stopping the progenitor cell-cycle during G-phase. The similarities between GDF11 and myostatin imply a likelihood that the same regulatory mechanisms are used to control tissue size during both muscular and neural development.

Cadherin-11 Recombinant Protein
91-753	ProSci	0.05 mg	EUR 542.75
Description: Cadherin-11 is a type II classical cadherin member of the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherins interact with themselves in a homophilic manner in connecting cells, and thus contribute to the sorting of heterogeneous cell types. Cadherin-11 contains five cadherin domains and is mainly expressed in the brain. Mature cadherin proteins consists of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small highly conserved C-terminal cytoplasmic domain. It is shown that Cadherin-11 is a viable molecular target for therapeutic intervention in Glioblastoma multiforme.

Collectin-11 Recombinant Protein
91-761	ProSci	0.05 mg	EUR 490.25
Description: Collectin-11 is a secreted protein that belongs to the COLEC10/COLEC11 family. Collectin-11 contains one C-type lectin domain and one collagen-like domain. Collectins play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating their recognition and removal. Collectin-11 binds to various sugars including fucose and mannose, but does not bind to glucose, N-acetylglucosamine and N-acetylgalactosamine. It has a higher affinity for fucose compared to mannose. Collectin-11 binds lipopolysaccharides (LPS). It also involved in fundamental development serving as a guidance cue for neural crest cell migration. Defects in Collectin-11 are the cause of 3MC syndrome type 2 (3MC2).

Cadherin-11 Recombinant Protein
91-809	ProSci	0.05 mg	EUR 490.25
Description: Cadherin-11, also known as OSF-4, Osteoblast cadherin and CDH11, is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherins interact with themselves in a homophilic manner in connecting cells, may thus contribute to the sorting of heterogeneous cell types. Cadherin-11 contains five cadherin domains and is mainly expressed in brain. Mature cadherin proteins consists of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. It is shown that cadherin-11 is a viable molecular target for therapeutic intervention in Glioblastoma multiforme.

IL-11 Recombinant Protein
92-457	ProSci	0.05 mg	EUR 542.75
Description: Interleukin-11(IL-11) is a secreted protein and belongs to the IL-6 superfamily. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-induced thrombocytopenia, induceacute phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cellproliferation and differentiation and could be use as a therapeutic for osteoporosis. IL-11 stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thickness and strength of long bones. In addition to having lymphopoietic/hematopoietic and osteotrophic properties, it has functions in many other tissues, including the brain, gut, testis and bone.

Recombinant Mouse Interleukin-11/IL-11 (C-Fc)
CJ59-10ug	Novoprotein	10ug	EUR 156
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse Interleukin-11/IL-11 (C-Fc)
CJ59-1mg	Novoprotein	1mg	EUR 2283
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse Interleukin-11/IL-11 (C-Fc)
CJ59-500ug	Novoprotein	500ug	EUR 1613
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse Interleukin-11/IL-11 (C-Fc)
CJ59-50ug	Novoprotein	50ug	EUR 369
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Mouse Regulator of G- protein signaling 11, Rgs11 ELISA KIT
ELI-14406m	Lifescience Market	96 Tests	EUR 865

TREM2 Recombinant Protein
11-127	ProSci	0.1 mg	EUR 595.25
Description: Triggering receptor expressed on myeloid cells 2 (TREM2) is a cell surface receptor of the immunoglobulin superfamily. The TREM2 is found in various tissue macrophages, such as CNS microglia, bone osteoclasts, alveolar, peritoneal and intestinal macrophages. TREM2 is also present on cultured bone marrow-derived macrophages and monocyte-derived dendritic cells. Some research have identified a rare variant of TREM2 that is a risk factor for Alzheimer disease (AD), which is the most common form of late-onset dementia.The extracellular region of TREM2 contains a single immunoglobulin superfamily domain and binds polyanionic ligands, such as bacterial lipopolysaccharide (LPS) and phospholipids8. Upon ligand binding, TREM2 transmits intracellular signals through an adaptor, DAP12 (also known as TYRO protein tyrosine kinase-binding protein (TYROBP)), which is associated with the transmembrane region of TREM2 and which recruits the protein tyrosine kinase SYK through its cytosolic immunoreceptor tyrosine-based activation motifs (ITAMs). TREM2 is a pro-tumorigenic marker of tumor-infiltrating macrophages in mouse models and human tumors that can be targeted to curb tumor growth and improve the efficacy of checkpoint blockade therapy while remodeling the landscape of tumor-infiltrating macrophages.

CD34 Recombinant Protein
11-132	ProSci	0.1 mg	EUR 684.5
Description: CD34 molecule is a cluster of differentiation molecule present on certain cells within the human body. It is a cell surface glycoprotein and functions as a cell-cell adhesion factor. It may also mediate the attachment of stem cells to bone marrow extracellular matrix or directly to stromal cells. As a ~ 110 kDa monomeric cell surface antigen, CD34 is highly glycosylated with nine potential N-linked and numerous potential O-linked glycosylation sites in its extracellular domain. The CD34 protein is a member of a family of single-pass transmembrane sialomucin proteins that show expression on early hematopoietic and vascular-associated tissue. CD34 is also an important adhesion molecule and is required for T cells to enter lymph nodes. It is expressed on lymph node endothelia whereas the L-selectin to which it binds is on the T cell. It was indicated that CD34 is a phosphorylation target for activated PKC, and couples to the hematopoietic adapter protein CrkL, which were involved in CD34 signaling pathways. CD34 is abberantly expressed in many kinds of tumors and is implicated in leukemogenesis.

PVRIG Recombinant Protein
11-134	ProSci	0.1 mg	EUR 595.25
Description: Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.

ZNRF3 Recombinant Protein
11-135	ProSci	0.1 mg	EUR 595.25
Description: The transmembrane E3 ubiquitin ligase zinc and ring finger 3 (ZNRF3) is a negative feedback regulator of Wnt signalling. ZNRF3 is associated with the Wnt receptor complex, and inhibits Wnt signalling by promoting the turnover of frizzled and LRP6 and acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway.

TREM2 Recombinant Protein
11-138	ProSci	0.1 mg	EUR 595.25
Description: Triggering receptor expressed on myeloid cells 2 (TREM2) is a cell surface receptor of the immunoglobulin superfamily. The TREM2 is found in various tissue macrophages, such as CNS microglia, bone osteoclasts, alveolar, peritoneal and intestinal macrophages. TREM2 is also present on cultured bone marrow-derived macrophages and monocyte-derived dendritic cells. Some research have identified a rare variant of TREM2 that is a risk factor for Alzheimer disease (AD), which is the most common form of late-onset dementia.The extracellular region of TREM2 contains a single immunoglobulin superfamily domain and binds polyanionic ligands, such as bacterial lipopolysaccharide (LPS) and phospholipids8. Upon ligand binding, TREM2 transmits intracellular signals through an adaptor, DAP12 (also known as TYRO protein tyrosine kinase-binding protein (TYROBP)), which is associated with the transmembrane region of TREM2 and which recruits the protein tyrosine kinase SYK through its cytosolic immunoreceptor tyrosine-based activation motifs (ITAMs). TREM2 is a pro-tumorigenic marker of tumor-infiltrating macrophages in mouse models and human tumors that can be targeted to curb tumor growth and improve the efficacy of checkpoint blockade therapy while remodeling the landscape of tumor-infiltrating macrophages.

TREM2 Recombinant Protein
11-139	ProSci	0.1 mg	EUR 595.25
Description: Triggering receptor expressed on myeloid cells 2 (TREM2) is a cell surface receptor of the immunoglobulin superfamily. The TREM2 is found in various tissue macrophages, such as CNS microglia, bone osteoclasts, alveolar, peritoneal and intestinal macrophages. TREM2 is also present on cultured bone marrow-derived macrophages and monocyte-derived dendritic cells. Some research have identified a rare variant of TREM2 that is a risk factor for Alzheimer disease (AD), which is the most common form of late-onset dementia.The extracellular region of TREM2 contains a single immunoglobulin superfamily domain and binds polyanionic ligands, such as bacterial lipopolysaccharide (LPS) and phospholipids8. Upon ligand binding, TREM2 transmits intracellular signals through an adaptor, DAP12 (also known as TYRO protein tyrosine kinase-binding protein (TYROBP)), which is associated with the transmembrane region of TREM2 and which recruits the protein tyrosine kinase SYK through its cytosolic immunoreceptor tyrosine-based activation motifs (ITAMs). TREM2 is a pro-tumorigenic marker of tumor-infiltrating macrophages in mouse models and human tumors that can be targeted to curb tumor growth and improve the efficacy of checkpoint blockade therapy while remodeling the landscape of tumor-infiltrating macrophages.

TREM2 Recombinant Protein
11-140	ProSci	0.1 mg	EUR 595.25
Description: Triggering receptor expressed on myeloid cells 2 (TREM2) is a cell surface receptor of the immunoglobulin superfamily. The TREM2 is found in various tissue macrophages, such as CNS microglia, bone osteoclasts, alveolar, peritoneal and intestinal macrophages. TREM2 is also present on cultured bone marrow-derived macrophages and monocyte-derived dendritic cells. Some research have identified a rare variant of TREM2 that is a risk factor for Alzheimer disease (AD), which is the most common form of late-onset dementia.The extracellular region of TREM2 contains a single immunoglobulin superfamily domain and binds polyanionic ligands, such as bacterial lipopolysaccharide (LPS) and phospholipids8. Upon ligand binding, TREM2 transmits intracellular signals through an adaptor, DAP12 (also known as TYRO protein tyrosine kinase-binding protein (TYROBP)), which is associated with the transmembrane region of TREM2 and which recruits the protein tyrosine kinase SYK through its cytosolic immunoreceptor tyrosine-based activation motifs (ITAMs). TREM2 is a pro-tumorigenic marker of tumor-infiltrating macrophages in mouse models and human tumors that can be targeted to curb tumor growth and improve the efficacy of checkpoint blockade therapy while remodeling the landscape of tumor-infiltrating macrophages.

PVRIG Recombinant Protein
11-148	ProSci	0.1 mg	EUR 595.25
Description: Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.