Leptin and fractalkine: Novel subcutaneous cytokines in burn injury

Leptin and fractalkine: Novel subcutaneous cytokines in burn injury

Burn damage is a pathology underpinned by progressive and aberrant irritation. It’s a main medical problem to survival and high quality of life. Whereas burn damage’s advanced native and disseminating pathological processes in the end stem from native tissue injury, thus far comparatively few research have tried to characterise the native inflammatory mediator profile.
Right here, cytokine content material and related transcriptional modifications have been measured in rat pores and skin for 3 hours instantly following induction of a scald-type (60°C, 2 minutes) burn damage mannequin. Leptin (p=0.0002) and fractalkine (p=0.0478) concentrations have been considerably elevated post-burn above pre-burn and management website values, coinciding with the event of burn website oedema and differential expression of leptin mRNA (p=0.0004).
Additional, gene sequencing enrichment evaluation indicated cytokine-cytokine receptor interplay (p=1.45×10-6). Subsequent behavioural research demonstrated that, following subcutaneous injection into the dorsum of the paw, each leptin and fractalkine induced mechanical allodynia, warmth hyperalgesia and the recruitment of macrophages.
That is the primary report of leptin’s elevation particularly on the burn website and the primary report of fractalkine’s elevation in any tissue post-burn which, along with the useful findings, requires exploration of the affect of those cytokines on ache, irritation and burn wound development. Moreover focusing on these signalling molecules represents a therapeutic potential as early formative mediators of those pathological processes.

Hepcidin Will increase Cytokines in Alzheimer’s Illness and Down’s Syndrome Dementia: Implication of Impaired Iron Homeostasis in Neuroinflammation

The liver-derived hormone hepcidin, a member of the defensin household of antimicrobial peptides, performs an vital position in host protection and innate immunity as a result of its broad antibacterial and antiviral properties. Ferritin, an iron storage protein is usually related to iron deficiency, hypoferritinemia, hypoxia, and immune issues, that are all vital issues for systemic an infection in Alzheimer’s illness (AD) and Down’s syndrome (DS) dementia.
Serum and autopsy mind samples have been collected from AD, DS and age-matched management topics. Serum samples have been analyzed with ELISA for ferritin, hepcidin and IL-6. Moreover, autopsy mind sections have been assessed by immunohistochemistry for iron-related and inflammatory proteins. A major enhance in serum hepcidin ranges was present in DS, in comparison with controls and AD topics (p < 0.0001).
Hepcidin protein was seen within the epithelial cells of choroid plexus, meningeal macrophages and within the astrocytes near the endothelium of blood vessels. Hepcidin co-localized with IL-6, indicating its anti-inflammatory properties. We discovered vital correlation between hypoferritinemia and elevated ranges of serum hepcidin in AD and DS. Hepcidin might be transported through macrophages and nearly all of the vesicular hepcidin enters the mind through a compromised blood mind barrier (BBB). Our findings present additional perception into the molecular implications of the altered iron metabolism in acute irritation, and may help in the direction of the event of preventive methods and novel remedies within the combat towards neuroinflammation.
 Leptin and fractalkine: Novel subcutaneous cytokines in burn injury

Case Report: A Case of Trimethoprim/Sulfamethoxazole-Triggered Hypotensive Shock: Cytokine Launch Syndrome Associated to Immune Checkpoint Inhibitors and Drug-Induced Hypersensitivity Syndrome

At the moment, only some stories exist on the cytokine launch syndrome (CRS) as one of many extreme immune-related adversarial occasions (irAEs) induced by immune checkpoint inhibitors (ICIs). Notably, it is extremely uncommon that grade Four CRS associated to ICI remedy overlaps with the drug-induced hypersensitivity syndrome (DiHS). A 46-year outdated girl with metastatic kidney most cancers had grade three interstitial pneumonitis induced by 4 cycles of mixture remedy of anti-programmed death-1 and anti-cytotoxic T lymphocyte-Four antibodies after proper cytoreductive nephrectomy.
Prophylactic administration of trimethoprim/sulfamethoxazole (TMP/SMX) was began concomitantly with prednisolone remedy to deal with the interstitial pneumonitis. She developed hypotensive shock when decreasing the dosage of prednisolone, and required intubation and air flow utilizing vasopressors on the intensive care unit.
She subsequently exhibited outstanding leukocytosis and an elevated stage of C-reactive protein, suggesting markedly elevated cytokine ranges. Curiously, facial edema and erythema elevated in affiliation with pyrexia, leukocytosis, liver dysfunction, and renal failure, suggesting that she developed DiHS. She obtained hemodialysis 3 times, a plasma alternate, and anti-interleukin-6 remedy to deal with extreme renal dysfunction, a thrombotic thrombocytopenic purpura-suspected situation, and potential grade Four CRS, respectively.

Recombinant Mouse Dedicator of cytokinesis protein 8 (Dock8) ,partial

RPC23284-100ug 100ug
EUR 572

Recombinant Mouse Dedicator of cytokinesis protein 8 (Dock8) ,partial

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EUR 2884.7

Recombinant Mouse Dedicator of cytokinesis protein 8 (Dock8) ,partial

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AP77352 each Ask for price

Recombinant Human Dedicator of cytokinesis protein 8(DOCK8),partial

AP77353 each Ask for price

Recombinant Human Dedicator of cytokinesis protein 8 (DOCK8) ,partial

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EUR 569.8

Recombinant Human Dedicator of cytokinesis protein 8 (DOCK8) ,partial

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EUR 353.4

Recombinant Human Dedicator of cytokinesis protein 8 (DOCK8) ,partial

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EUR 569.8

Recombinant Human Dedicator of cytokinesis protein 8 (DOCK8) ,partial

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EUR 353.4

Recombinant Dedicator Of Cytokinesis 7 (DOCK7)

RPU58286-100ug 100ug
EUR 537.6

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EUR 537.6

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Recombinant Dedicator Of Cytokinesis 5 (DOCK5)

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EUR 470.4

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EUR 470.4

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EUR 2184

Recombinant Dedicator Of Cytokinesis 7 (DOCK7)

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Recombinant Dedicator Of Cytokinesis 9 (DOCK9)

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EUR 470.4

Recombinant Dedicator Of Cytokinesis 9 (DOCK9)

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EUR 2184

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RPU57885-100ug 100ug
EUR 510.8

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RPU57885-1mg 1mg
EUR 2371.2

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EUR 418

Recombinant Dedicator Of Cytokinesis 1 (DOCK1)

RPG175Hu01 10ug
EUR 164

Recombinant Dedicator Of Cytokinesis 1 (DOCK1)

4-RPG175Hu01
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Description: Recombinant Human Dedicator Of Cytokinesis 1 expressed in: E.coli

Recombinant Dedicator Of Cytokinesis 6 (DOCK6)

RPG176Mu01 10ug
EUR 140

Recombinant Dedicator Of Cytokinesis 7 (DOCK7)

RPG177Hu01 10ug
EUR 160

Recombinant Dedicator Of Cytokinesis 7 (DOCK7)

RPG177Ra01 10ug
EUR 140

Recombinant Dedicator Of Cytokinesis 9 (DOCK9)

RPG179Ra01 10ug
EUR 140

Recombinant Dedicator Of Cytokinesis 2 (DOCK2)

RPG182Hu01 10ug
EUR 160

Recombinant Dedicator Of Cytokinesis 2 (DOCK2)

4-RPG182Hu01
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Description: Recombinant Human Dedicator Of Cytokinesis 2 expressed in: E.coli

Recombinant Dedicator Of Cytokinesis 4 (DOCK4)

RPG184Hu01 10ug
EUR 164

Recombinant Dedicator Of Cytokinesis 4 (DOCK4)

4-RPG184Hu01
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Description: Recombinant Human Dedicator Of Cytokinesis 4 expressed in: E.coli

Recombinant Dedicator Of Cytokinesis 5 (DOCK5)

RPG185Hu01 10ug
EUR 160

Recombinant Dedicator Of Cytokinesis 5 (DOCK5)

RPG185Mu01 10ug
EUR 152

Recombinant Dedicator Of Cytokinesis 2 (DOCK2)

RPU51615-100ug 100ug
EUR 492.8

Recombinant Dedicator Of Cytokinesis 2 (DOCK2)

RPU51615-1mg 1mg
EUR 2184

Recombinant Dedicator Of Cytokinesis 2 (DOCK2)

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EUR 396

Recombinant Dedicator Of Cytokinesis 4 (DOCK4)

RPU51889-100ug 100ug
EUR 504.9

Recombinant Dedicator Of Cytokinesis 4 (DOCK4)

RPU51889-1mg 1mg
EUR 2238.6

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EUR 405.9

Recombinant Dedicator Of Cytokinesis 1 (DOCK1)

RPU41150-100ug 100ug
EUR 504.9

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RPU41150-1mg 1mg
EUR 2238.6

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EUR 405.9

Recombinant Dedicator Of Cytokinesis 10 (DOCK10)

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EUR 537.6

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EUR 2496

Recombinant Dedicator Of Cytokinesis 10 (DOCK10)

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EUR 418

Recombinant Dedicator Of Cytokinesis 10 (DOCK10)

RPU57507-100ug 100ug
EUR 470.4

Recombinant Dedicator Of Cytokinesis 10 (DOCK10)

RPU57507-1mg 1mg
EUR 2184

Recombinant Dedicator Of Cytokinesis 10 (DOCK10)

RPU57507-50ug 50ug
EUR 385

Recombinant Dedicator Of Cytokinesis 10 (DOCK10)

RPG180Hu01 10ug
EUR 160

Recombinant Dedicator Of Cytokinesis 10 (DOCK10)

RPG180Mu01 10ug
EUR 140

Mouse Dedicator of cytokinesis protein 11, Dock11 ELISA KIT

ELI-08041m 96 Tests
EUR 1038

Mouse Dedicator of cytokinesis protein 11 (DOCK11) ELISA Kit

abx510779-96tests 96 tests
EUR 687.5

Mouse Dedicator of cytokinesis protein 8 (Dock8)

1-CSB-YP807451MO1
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Description: Recombinant Mouse Dedicator of cytokinesis protein 8(Dock8),partial expressed in Yeast

Mouse Dedicator of cytokinesis protein 8 (Dock8)

1-CSB-EP807451MO
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Description: Recombinant Mouse Dedicator of cytokinesis protein 8(Dock8),partial expressed in E.coli

Mouse Dedicator of cytokinesis protein 8 (Dock8)

1-CSB-EP807451MO1
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Description: Recombinant Mouse Dedicator of cytokinesis protein 8(Dock8),partial expressed in E.coli

Dedicator of Cytokinesis Protein 11 (DOCK11) Antibody

20-abx007957
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Dedicator of Cytokinesis Protein 11 (DOCK11) Antibody

20-abx219454
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Mouse Dedicator of cytokinesis protein 1(DOCK1) Elisa kit

EK730733 96 Wells
EUR 0.71

Mouse Dedicator of cytokinesis protein 1, Dock1 ELISA KIT

ELI-47076m 96 Tests
EUR 1038

Mouse Dedicator of cytokinesis protein 2, Dock2 ELISA KIT

ELI-47799m 96 Tests
EUR 1038

Mouse Dedicator of cytokinesis protein 7, Dock7 ELISA KIT

ELI-32144m 96 Tests
EUR 1038

Mouse Dedicator of cytokinesis protein 6, Dock6 ELISA KIT

ELI-32830m 96 Tests
EUR 1038

Mouse Dedicator of cytokinesis protein 9, Dock9 ELISA KIT

ELI-26224m 96 Tests
EUR 1038

Mouse Dedicator of cytokinesis protein 4, Dock4 ELISA KIT

ELI-26847m 96 Tests
EUR 1038

Mouse Dedicator of cytokinesis protein 5, Dock5 ELISA KIT

ELI-26848m 96 Tests
EUR 1038

Mouse Dedicator of cytokinesis protein 3, Dock3 ELISA KIT

ELI-09219m 96 Tests
EUR 1038

Mouse Dedicator of cytokinesis protein 8, Dock8 ELISA KIT

ELI-09684m 96 Tests
EUR 1038

Mouse Dedicator of cytokinesis protein 1 (DOCK1) ELISA Kit

abx510788-96tests 96 tests
EUR 687.5

Mouse Dedicator of cytokinesis protein 2 (DOCK2) ELISA Kit

abx510790-96tests 96 tests
EUR 687.5

Mouse Dedicator of cytokinesis protein 3 (DOCK3) ELISA Kit

abx510792-96tests 96 tests
EUR 687.5

Mouse Dedicator of cytokinesis protein 4 (DOCK4) ELISA Kit

abx510794-96tests 96 tests
EUR 687.5

Mouse Dedicator of cytokinesis protein 5 (DOCK5) ELISA Kit

abx510796-96tests 96 tests
EUR 687.5

Mouse Dedicator of cytokinesis protein 6 (DOCK6) ELISA Kit

abx510798-96tests 96 tests
EUR 687.5

Mouse Dedicator of cytokinesis protein 7 (DOCK7) ELISA Kit

abx510800-96tests 96 tests
EUR 687.5

Mouse Dedicator of cytokinesis protein 8 (DOCK8) ELISA Kit

abx510802-96tests 96 tests
EUR 687.5

Mouse Dedicator of cytokinesis protein 9 (DOCK9) ELISA Kit

abx510804-96tests 96 tests
EUR 687.5

Human Dedicator of cytokinesis protein 11, DOCK11 ELISA KIT

ELI-46899h 96 Tests
EUR 988.8

Human Dedicator of cytokinesis protein 11 (DOCK11) ELISA Kit

abx510778-96tests 96 tests
EUR 687.5

Mouse Dedicator of cytokinesis protein 10, Dock10 ELISA KIT

ELI-31732m 96 Tests
EUR 1038

Mouse Dedicator of cytokinesis protein 10 (DOCK10) ELISA Kit

abx510777-96tests 96 tests
EUR 687.5

Mouse Dedicator of cytokinesis Protein 1, DOCK1 GENLISA ELISA

KLM1998 1 x 96 wells
EUR 341

Human Dedicator of cytokinesis protein 8 (DOCK8)

1-CSB-YP836734HU
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Description: Recombinant Human Dedicator of cytokinesis protein 8(DOCK8),partial expressed in Yeast

Human Dedicator of cytokinesis protein 8 (DOCK8)

1-CSB-YP836734HUb0
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Description: Recombinant Human Dedicator of cytokinesis protein 8(DOCK8),partial expressed in Yeast

Dedicator of Cytokinesis Protein 5 (DOCK5) Antibody

abx122686-100ug 100 ug
EUR 469.2

Dedicator of Cytokinesis Protein 5 (DOCK5) Antibody

20-abx311377
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DOCK4 Antibody / Dedicator of cytokinesis protein 4

RQ7372 100ug
EUR 419

Dedicator of Cytokinesis Protein 5 (DOCK5) Antibody

abx122686-100l 100 µl Ask for price

Dedicator of Cytokinesis Protein 5 (DOCK5) Antibody

abx122686-20l 20 µl
EUR 337.5

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abx122686-50l 50 µl Ask for price

Dedicator Of Cytokinesis Protein 1 (DOCK1) Antibody

abx232492-100g 100 µg
EUR 350

Dedicator of Cytokinesis Protein 5 (DOCK5) Antibody

abx311377-100g 100 µg
EUR 362.5

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abx311377-20g 20 µg
EUR 162.5

Dedicator of Cytokinesis Protein 5 (DOCK5) Antibody

abx311377-50g 50 µg
EUR 250

Dedicator of Cytokinesis Protein 10 (DOCK10) Antibody

abx145342-100ug 100 ug
EUR 469.2

Dedicator of Cytokinesis Protein 10 (DOCK10) Antibody

20-abx301562
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Dedicator of Cytokinesis Protein 10 (DOCK10) Antibody

abx301562-100g 100 µg
EUR 362.5

Dedicator of Cytokinesis Protein 10 (DOCK10) Antibody

abx301562-20g 20 µg
EUR 162.5

Dedicator of Cytokinesis Protein 10 (DOCK10) Antibody

abx301562-50g 50 µg
EUR 250

Dedicator of Cytokinesis Protein 10 (DOCK10) Antibody

abx145342-1096tests 10 × 96 tests Ask for price

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abx145342-596tests 5 × 96 tests Ask for price

Dedicator of Cytokinesis Protein 10 (DOCK10) Antibody

abx145342-96tests 96 tests
EUR 337.5

Human Dedicator Of Cytokinesis 1 (DOCK1) Protein

20-abx066282
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Human Dedicator Of Cytokinesis 4 (DOCK4) Protein

20-abx168105
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Human Dedicator Of Cytokinesis 2 (DOCK2) Protein

20-abx166509
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Human Dedicator Of Cytokinesis 3 (DOCK3) Protein

20-abx653130
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Human Dedicator Of Cytokinesis 2 (DOCK2) Protein

abx166509-100g 100 µg
EUR 537.5

Human Dedicator Of Cytokinesis 2 (DOCK2) Protein

abx166509-10g 10 µg
EUR 212.5

Human Dedicator Of Cytokinesis 2 (DOCK2) Protein

abx166509-50g 50 µg
EUR 375

Human Dedicator Of Cytokinesis 4 (DOCK4) Protein

abx168105-100l 100 µl
EUR 212.5

Human Dedicator Of Cytokinesis 4 (DOCK4) Protein

abx168105-1ml 1 ml
EUR 537.5

Human Dedicator Of Cytokinesis 4 (DOCK4) Protein

abx168105-200l 200 µl
EUR 375

Human Dedicator Of Cytokinesis 1 (DOCK1) Protein

abx066282-100g 100 µg
EUR 537.5

Human Dedicator Of Cytokinesis 1 (DOCK1) Protein

abx066282-10g 10 µg
EUR 212.5

Human Dedicator Of Cytokinesis 1 (DOCK1) Protein

abx066282-50g 50 µg
EUR 375

Human Dedicator Of Cytokinesis 3 (DOCK3) Protein

abx653130-100g 100 µg
EUR 4525

Human Dedicator Of Cytokinesis 3 (DOCK3) Protein

abx653130-200g 200 µg Ask for price

Human Dedicator Of Cytokinesis 3 (DOCK3) Protein

abx653130-50g 50 µg
EUR 1800

Dock11 (untagged) - Mouse dedicator of cytokinesis 11 (Dock11), (10ug)

MC225158 10 µg Ask for price

Human Dedicator Of Cytokinesis Protein 1 (DOCK1) ELISA Kit

abx259546-96tests 96 tests
EUR 1093.2

Human Dedicator Of Cytokinesis Protein 6 (DOCK6) ELISA Kit

abx386963-96tests 96 tests
EUR 1093.2

Human Dedicator Of Cytokinesis Protein 7 (DOCK7) ELISA Kit

abx386964-96tests 96 tests
EUR 1093.2

Human Dedicator Of Cytokinesis Protein 8 (DOCK8) ELISA Kit

abx386965-96tests 96 tests
EUR 1093.2

Human Dedicator Of Cytokinesis Protein 9 (DOCK9) ELISA Kit

abx386966-96tests 96 tests
EUR 1093.2

Human Dedicator of cytokinesis protein 4(DOCK4) Elisa Kit

EK712124 96 Wells
EUR 0.24

Human Dedicator of cytokinesis protein 1(DOCK1) Elisa Kit

EK712125 96 Wells
EUR 0.24

Human Dedicator of cytokinesis protein 2, DOCK2 ELISA KIT

ELI-46901h 96 Tests
EUR 988.8

Human Dedicator of cytokinesis protein 7, DOCK7 ELISA KIT

ELI-31733h 96 Tests
EUR 988.8

Human Dedicator of cytokinesis protein 3, DOCK3 ELISA KIT

ELI-32143h 96 Tests
EUR 988.8

Human Dedicator of cytokinesis protein 6, DOCK6 ELISA KIT

ELI-26222h 96 Tests
EUR 988.8

Human Dedicator of cytokinesis protein 9, DOCK9 ELISA KIT

ELI-26223h 96 Tests
EUR 988.8

Human Dedicator of cytokinesis protein 4, DOCK4 ELISA KIT

ELI-08843h 96 Tests
EUR 988.8

Human Dedicator of cytokinesis protein 1, DOCK1 ELISA KIT

ELI-09218h 96 Tests
EUR 988.8

Human Dedicator of cytokinesis protein 5, DOCK5 ELISA KIT

ELI-09220h 96 Tests
EUR 988.8

Human Dedicator of cytokinesis protein 8, DOCK8 ELISA KIT

ELI-09221h 96 Tests
EUR 988.8

Human Dedicator of cytokinesis protein 4 (DOCK4) ELISA Kit

EK10543 96Т
EUR 799

Human Dedicator of cytokinesis protein 3 (DOCK3) ELISA Kit

EK10544 96Т
EUR 799

Human Dedicator of cytokinesis protein 4 (DOCK4) ELISA Kit

AE46810HU-48Tests 48 Tests
EUR 325
Description: Human (Homo sapiens)

Human Dedicator of cytokinesis protein 4 (DOCK4) ELISA Kit

AE46810HU-96Tests 96 Tests
EUR 610
Description: Human (Homo sapiens)

Human Dedicator of cytokinesis protein 3 (DOCK3) ELISA Kit

AE46812HU-48Tests 48 Tests
EUR 325
Description: Human (Homo sapiens)

Human Dedicator of cytokinesis protein 3 (DOCK3) ELISA Kit

AE46812HU-96Tests 96 Tests
EUR 610
Description: Human (Homo sapiens)

Human Dedicator Of Cytokinesis Protein 1 (DOCK1) ELISA Kit

abx259546-1mg 1 mg Ask for price

Human Dedicator Of Cytokinesis Protein 1 (DOCK1) ELISA Kit

abx259546-20g 20 µg Ask for price

Human Dedicator Of Cytokinesis Protein 1 (DOCK1) ELISA Kit

abx259546-5g 5 µg
EUR 687.5

Human Dedicator of cytokinesis protein 2 (DOCK2) ELISA Kit

abx510789-96tests 96 tests
EUR 687.5

Human Dedicator of cytokinesis protein 5 (DOCK5) ELISA Kit

abx510795-96tests 96 tests
EUR 687.5

Human Dedicator of cytokinesis protein 10, DOCK10 ELISA KIT

ELI-47075h 96 Tests
EUR 988.8

Human Dedicator of cytokinesis protein 10 (DOCK10) ELISA Kit

abx510776-96tests 96 tests
EUR 687.5

Dock11 (GFP-tagged) - Mouse dedicator of cytokinesis 11 (Dock11), (10ug)

MG218928 10 µg Ask for price

Dock11 (Myc-DDK-tagged) - Mouse dedicator of cytokinesis 11 (Dock11)

MR218928 10 µg Ask for price

Human Dedicator of cytokinesis Protein 1, DOCK1 GENLISA ELISA

KBH5173 1 x 96 wells
EUR 286

ELISA kit for Human Dedicator of cytokinesis protein 4 (DOCK4)

KTE61990-48T 48T
EUR 398.4
Description: Quantitative sandwich ELISA for measuring Human Dedicator of cytokinesis protein 4 (DOCK4) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Dedicator of cytokinesis protein 4 (DOCK4)

KTE61990-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Human Dedicator of cytokinesis protein 4 (DOCK4) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Dedicator of cytokinesis protein 4 (DOCK4)

KTE61990-96T 96T
EUR 646.8
Description: Quantitative sandwich ELISA for measuring Human Dedicator of cytokinesis protein 4 (DOCK4) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Dedicator of cytokinesis protein 3 (DOCK3)

KTE61991-48T 48T
EUR 398.4
Description: Quantitative sandwich ELISA for measuring Human Dedicator of cytokinesis protein 3 (DOCK3) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Dedicator of cytokinesis protein 3 (DOCK3)

KTE61991-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Human Dedicator of cytokinesis protein 3 (DOCK3) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Dedicator of cytokinesis protein 3 (DOCK3)

KTE61991-96T 96T
EUR 646.8
Description: Quantitative sandwich ELISA for measuring Human Dedicator of cytokinesis protein 3 (DOCK3) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Dock11 (untagged) - Rat dedicator of cytokinesis 11 (Dock11)

RN217735 10 µg Ask for price

DOCK11 (untagged)-Human dedicator of cytokinesis 11 (DOCK11)

SC309120 10 µg Ask for price

Dedicator of Cytokinesis 1 (DOCK1) Antibody

20-abx112009
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  • 150 ul
  • 50 ul

Dedicator of Cytokinesis 2 (DOCK2) Antibody

20-abx112010
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  • 150 ul
  • 50 ul

Dedicator of Cytokinesis 3 (DOCK3) Antibody

20-abx112011
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  • 150 ul
  • 50 ul

Dedicator of Cytokinesis 1 (DOCK1) Antibody

20-abx102732
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Dedicator of Cytokinesis 2 (DOCK2) Antibody

20-abx129016
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Dedicator of Cytokinesis 4 (DOCK4) Antibody

20-abx129252
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Dedicator of Cytokinesis 2 (DOCK2) Antibody

20-abx126888
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  • 100 ul
  • 200 ul

Dedicator of Cytokinesis 1 (DOCK1) Antibody

abx147652-100ug 100 ug
EUR 526.8

Dedicator of Cytokinesis 2 (DOCK2) Antibody

20-abx149900
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  • 100 ug
  • 50 ug

Dedicator of Cytokinesis 1 (DOCK1) Antibody

20-abx014419
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  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
Though these therapies didn’t elicit ample results, high-dose administration of intravenous immunoglobulin was profitable. With steroid mini-pulse remedy and the next administration of prednisolone, she recovered efficiently. To the very best of our information, that is the primary report that ICIs and TMP/SMX can induce hypotensive shock accompanied with CRS and DiHS throughout immunosuppressive remedy for an irAE. Importantly, the prophylactic administration of TMP/SMX needs to be carried out cautiously to keep away from extreme drug reactions reminiscent of CRS or DiHS.

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