Impact of mono-culture vs. Co-culture of keratinocytes and monocytes on cytokine responses induced by important skin sensitizers

Impact of mono-culture vs. Co-culture of keratinocytes and monocytes on cytokine responses induced by important skin sensitizers

Sensitization to a contact allergen brings with it a lifelong threat to develop allergic contact dermatitis. Irritation is a crucial a part of the pores and skin sensitizing mechanism, and understanding how totally different haptens stimulate the immune system, in addition to the position performed by totally different cell varieties current in pores and skin, could also be useful for growing optimized in vitro fashions for threat evaluation of recent chemical compounds or mixtures.
The intention of this examine was to check the cytokine profile following publicity of cells representing keratinocytes (HaCaT), monocytes (THP-1) and a co-culture of those cells to a few clinically essential pores and skin sensitizers: cobalt (II) chloride (CoCl2), methylisothiazolinone (MI) and p-phenylenediamine (PPD). Secretion of ten pro-inflammatory cytokines was measured utilizing multiplexing.
The outcomes confirmed that the cytokine response differed considerably between the three cell assays. CoCl2 triggered a rise of IL-Eight in HaCaT cells, whereas the induction of additionally IL-13 and IL-1β was noticed in THP-1 cells and co-cultures. MI induced six cytokines in HaCaT cells however solely IL-1β within the THP-1 cells and 4 cytokines within the co-culture. Curiously, the IL-1β response was large within the co-culture.
PPD triggered launch of IL-1β in all three fashions in addition to IL-Eight within the co-culture. Management experiments with two non-sensitizers and irritants (lactic acid and sodium dodecyl sulfate) confirmed no impact on IL-Eight or IL-1β within the co-culture. Taken collectively, outcomes from this exploratory evaluation present distinctive cytokine profiles depending on the kind of hapten and cell mannequin. Importantly, all three haptens triggered secretion of IL-1β and IL-Eight in a co-culture of HaCaT cells and THP-1 cells, representing probably the most sturdy check system.

Evaluation of cytokine threat components within the early loss of life of sufferers with secondary phagocytic lymphocytic histiocytosis

Secondary hemophagocytic lymphohistiocytosis (sHLH) is an extreme inflammatory response syndrome brought on by immune abnormalities. Updated, the chance components for cytokines inflicting early loss of life in sHLH sufferers haven’t been elucidated. Our examine reviewed the cytokine expression ranges in peripheral blood of 50 sHLH sufferers.
By means of Cox proportional hazard mannequin evaluation, we discovered that IL-17F ≥2.835 pg/mL (HR = 5.922, 95% CI = 1.793-19.558, P = 0.004) was an unbiased loss of life threat think about sHLH sufferers, and it was additionally 30 days (Cutoff-value = 2.890 pg/mL, HR = 16.568, 95% CI = 1.917-143.195, P = 0.011), 60 days (Cutoff-value = 2.890 pg/mL, HR = 7.559, 95% CI = 1.449-39.423, P = 0.016), 90 day loss of life threat issue (Cutoff-value = 2.835 pg/mL, HR = 7.649, 95% CI = 1.965-29.778, P = 0.003); IL-10 ≥16.730 pg/mL (HR = 4.821, 95% CI = 1.151-20.116, P = 0.031) will not be solely a loss of life threat issue inside 90 days, but additionally inside 10 days (Cutoff-value = 944.350 pg/mL, HR = 13.321, 95% CI = 1.123-158.03, P = 0.027); and IL-5 ≥2.495 pg/mL (HR = 15.687, 95% CI = 1.377-178.645, P = 0.04) was additionally a loss of life threat issue inside 10 days.
In addition to, IL-17F, IL-10, IL-5, and the beforehand reported widespread threat components Age, platelets, activated partial thromboplastin time, triglyceride, and lactate dehydrogenase have been analyzed collectively. It was discovered that the affected person age ≥56 years-old is was an essential threat issue for loss of life inside 30 days, IL-17 ≥2.89 pg/mL and IL-10 ≥16.73 pg/mL are essential threat components for affected person loss of life. In abstract, our knowledge point out that age, IL-10 and IL-17F are essential threat components for early loss of life in sHLH sufferers.

Intragastric and atomized administration of canagliflozin inhibit inflammatory cytokine storm in lipopolysaccharide-treated sepsis in mice: A possible COVID-19 remedy

Thus far, medication to attenuate cytokine storm in extreme instances of Corona Virus Illness 2019 (COVID-19) will not be accessible. On this examine, we investigated the results of intragastric and atomized administration of canagliflozin (CAN) on cytokine storm in lung tissues of lipopolysaccharides (LPS)-induced mice. Outcomes confirmed that intragastric administration of CAN considerably and extensively inhibited the manufacturing of inflammatory cytokines in lung tissues of LPS-induced sepsis mice. Concurrently, intragastric administration of CAN considerably improved inflammatory pathological modifications of lung tissues.
 Impact of mono-culture vs. Co-culture of keratinocytes and monocytes on cytokine responses induced by important skin sensitizers
Atomized administration of CAN additionally exhibited related results in LPS-induced sepsis mice. Moreover, CAN considerably inhibited hypoxia inducible issue 1α (HIF-1α) and phosphofructokinase-2/fructose-2,6-bisphosphatase 3 (PFKFB3) protein ranges in LPS-treated lung tissues. These outcomes indicated that CAN may attenuate cytokine storm and cut back the inflammatory signs in vital instances in COVID-19. Its motion mechanism may contain the regulation of HIF-1α and glycolysis in vivo. Nevertheless, additional research about medical software and mechanism evaluation ought to be validated sooner or later.

Egg white peptides ameliorate dextran sulfate sodium-induced acute colitis signs by inhibiting the manufacturing of pro-inflammatory cytokines and modulation of intestine microbiota composition

Egg white peptides (EWPs) could be successfully used to alleviate and deal with inflammatory ailments on account of their anti-oxidation, anti-inflammation, and microbiota regulation capabilities. A dextran sodium sulfate (DSS)-induced colitis mannequin was used to make clear the regulatory results of EWPs on colitis.
Forty-three peptide sequences have been recognized from EWPs utilizing LC-MS/MS. The outcomes demonstrated that EWPs decreased the degrees of pro-inflammatory cytokines and the extent of crypt harm in a dose-dependent method. 16S rRNA gene sequencing outcomes indicated that 200 mg/kg EWPs considerably elevated the relative abundance of helpful micro organism Lactobacillus and Candidatus_Saccharimonas, and lowered the relative abundance of pathogenic micro organism Ruminiclostridium and Akkermansia.

Recombinant Saccharomyces cerevisiae Carboxypeptidase Y inhibitor (TFS1)

MBS1109205-01mgEColi 0.1mg(E-Coli)
EUR 870

Recombinant Saccharomyces cerevisiae Carboxypeptidase Y inhibitor (TFS1)

MBS1109205-01mgYeast 0.1mg(Yeast)
EUR 1045

Rabbit anti Saccharomyces cerevisiae Carboxypeptidase Y

MBS573714-1mg 1mg
EUR 715

Rabbit anti Saccharomyces cerevisiae Carboxypeptidase Y

MBS573714-5x1mg 5x1mg
EUR 3080

Rabbit anti Saccharomyces cerevisiae Carboxypeptidase Y

MBS573738-10mg 10mg
EUR 325

Rabbit anti Saccharomyces cerevisiae Carboxypeptidase Y

MBS573738-5x10mg 5x10mg
EUR 1320

Recombinant Saccharomyces cerevisiae Carboxypeptidase Y-deficient protein 8 (PEP8)

MBS1148637-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1250

Recombinant Saccharomyces cerevisiae Carboxypeptidase Y-deficient protein 8 (PEP8)

MBS1148637-002mgEColi 0.02mg(E-Coli)
EUR 920

Recombinant Saccharomyces cerevisiae Carboxypeptidase Y-deficient protein 8 (PEP8)

MBS1148637-002mgYeast 0.02mg(Yeast)
EUR 1045

Recombinant Saccharomyces cerevisiae Carboxypeptidase Y-deficient protein 8 (PEP8)

MBS1148637-01mgEColi 0.1mg(E-Coli)
EUR 1105

Recombinant Saccharomyces cerevisiae Carboxypeptidase Y-deficient protein 8 (PEP8)

MBS1148637-01mgYeast 0.1mg(Yeast)
EUR 1190

Recombinant Saccharomyces cerevisiae Carboxypeptidase S (CPS1) , partial

MBS1169902-INQUIRE INQUIRE Ask for price

Recombinant Saccharomyces cerevisiae Putative carboxypeptidase YOL153C (YOL153C) , partial

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Rabbit anti Saccharomyces cerevisiae Carboxypeptidase Y, conjugated with Biotin

MBS573426-1mL 1mL
EUR 545

Rabbit anti Saccharomyces cerevisiae Carboxypeptidase Y, conjugated with Biotin

MBS573426-5x1mL 5x1mL
EUR 2305

Recombinant Saccharomyces cerevisiae Putative serine carboxypeptidase YBR139W (YBR139W) , partial

MBS1007988-INQUIRE INQUIRE Ask for price

Recombinant Saccharomyces cerevisiae Pheromone-processing carboxypeptidase KEX1 (KEX1), partial

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Recombinant Saccharomyces cerevisiae Pheromone-processing carboxypeptidase KEX1 (KEX1) , partial

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Recombinant Saccharomyces cerevisiae Pheromone-processing carboxypeptidase KEX1 (KEX1), partial

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Recombinant Saccharomyces cerevisiae Pheromone-processing carboxypeptidase KEX1 (KEX1), partial

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Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1

MBS1208393-002mgEColi 0.02mg(E-Coli)
EUR 375

Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1

MBS1208393-002mgYeast 0.02mg(Yeast)
EUR 420

Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1

MBS1208393-01mgEColi 0.1mg(E-Coli)
EUR 635

Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1

MBS1208393-01mgYeast 0.1mg(Yeast)
EUR 695

Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1

MBS1208393-05mgYeast 0.5mg(Yeast)
EUR 1505

Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1

MBS9420878-002mg 0.02mg
EUR 460

Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1

MBS9420878-01mg 0.1mg
EUR 795

Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1

MBS9420878-1mg 1mg
EUR 2525

Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1

MBS9420878-5x1mg 5x1mg
EUR 11205

Native Baker's yeast (S. cerevisiae) Carboxypeptidase Y

NATE-0103 1 mg
EUR 790
Description: > 10u/mg

Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1 (PYC1)

MBS9422594-002mg 0.02mg
EUR 505

Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1 (PYC1)

MBS9422594-01mg 0.1mg
EUR 895

Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1 (PYC1)

MBS9422594-05mg 0.5mg
EUR 1975

Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1 (PYC1)

MBS9422594-5x05mg 5x0.5mg
EUR 8735

Recombinant Saccharomyces Cerevisiae Acetyl-CoA Carboxylase (ACC1), Partial

MBS7115273-002mgEColi 0.02mg(E-Coli)
EUR 375

Recombinant Saccharomyces Cerevisiae Acetyl-CoA Carboxylase (ACC1), Partial

MBS7115273-02mgEColi 0.2mg(E-Coli)
EUR 985

Recombinant Saccharomyces Cerevisiae Acetyl-CoA Carboxylase (ACC1), Partial

MBS7115273-5x02mgEColi 5x0.2mg(E-Coli)
EUR 4195

Recombinant Saccharomyces Cerevisiae Acetyl-CoA Carboxylase (ACC1), Partial

MBS7115274-002mgEColi 0.02mg(E-Coli)
EUR 375

Recombinant Saccharomyces Cerevisiae Acetyl-CoA Carboxylase (ACC1), Partial

MBS7115274-02mgEColi 0.2mg(E-Coli)
EUR 985

Recombinant Saccharomyces Cerevisiae Acetyl-CoA Carboxylase (ACC1), Partial

MBS7115274-5x02mgEColi 5x0.2mg(E-Coli)
EUR 4195

Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 2 (PYC2) , partial

MBS1033269-INQUIRE INQUIRE Ask for price

Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1(PYC1) ,partial

AP70995 1mg
EUR 2826

Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1(PYC1),partial

AP72889 each Ask for price

Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1 (PYC1), partial

CSB-YP319972SVG 6175 mg Ask for price

Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1 (PYC1), partial

CSB-YP319972SVG-20ug 20ug Ask for price
Description: 18-470aa

Recombinant Saccharomyces cerevisiae Acetyl-CoA carboxylase (ACC1), partial

CSB-EP2725SVG1 2576 mg Ask for price

Recombinant Saccharomyces cerevisiae Acetyl-CoA carboxylase (ACC1), partial

CSB-EP2725SVG1-20ug 20ug Ask for price
Description: 217-775aa

Recombinant Saccharomyces cerevisiae Acetyl-CoA carboxylase (ACC1), partial

CSB-EP2725SVG2 2577 mg Ask for price

Recombinant Saccharomyces cerevisiae Acetyl-CoA carboxylase (ACC1), partial

CSB-EP2725SVG2-20ug 20ug Ask for price
Description: 2-581aa

Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1 (PYC1), partial

CSB-EP319972SVG 2798 mg Ask for price

Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1 (PYC1), partial

CSB-EP319972SVG-20ug 20ug Ask for price
Description: 18-470aa

OPCA00268-1MG - Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1

OPCA00268-1MG 1mg
EUR 1977

OPCA00268-100UG - Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1

OPCA00268-100UG 100ug
EUR 586

OPCA00268-20UG - Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1

OPCA00268-20UG 20ug
EUR 400

Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 16 (UBP16)

MBS1119031-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1365

Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 16 (UBP16)

MBS1119031-002mgEColi 0.02mg(E-Coli)
EUR 1065

Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 16 (UBP16)

MBS1119031-002mgYeast 0.02mg(Yeast)
EUR 1125

Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 16 (UBP16)

MBS1119031-01mgEColi 0.1mg(E-Coli)
EUR 1245

Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 16 (UBP16)

MBS1119031-01mgYeast 0.1mg(Yeast)
EUR 1320

Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 8 (UBP8)

MBS1085042-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1335

Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 8 (UBP8)

MBS1085042-002mgEColi 0.02mg(E-Coli)
EUR 1030

Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 8 (UBP8)

MBS1085042-002mgYeast 0.02mg(Yeast)
EUR 1130

Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 8 (UBP8)

MBS1085042-01mgEColi 0.1mg(E-Coli)
EUR 1205

Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 8 (UBP8)

MBS1085042-01mgYeast 0.1mg(Yeast)
EUR 1290

Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 6 (UBP6)

MBS1261319-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1365

Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 6 (UBP6)

MBS1261319-002mgEColi 0.02mg(E-Coli)
EUR 1065

Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 6 (UBP6)

MBS1261319-002mgYeast 0.02mg(Yeast)
EUR 1125

Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 6 (UBP6)

MBS1261319-01mgEColi 0.1mg(E-Coli)
EUR 1245

Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 6 (UBP6)

MBS1261319-01mgYeast 0.1mg(Yeast)
EUR 1320

Recombinant Saccharomyces cerevisiae Aminopeptidase Y (APE3)

MBS1005634-002mgEColi 0.02mg(E-Coli)
EUR 375

Recombinant Saccharomyces cerevisiae Aminopeptidase Y (APE3)

MBS1005634-01mgEColi 0.1mg(E-Coli)
EUR 635

Recombinant Saccharomyces cerevisiae Aminopeptidase Y (APE3)

MBS1005634-1mgEColi 1mg(E-Coli)
EUR 1925

Recombinant Saccharomyces cerevisiae Aminopeptidase Y (APE3)

MBS1005634-5x1mgEColi 5x1mg(E-Coli)
EUR 8405

Recombinant Saccharomyces cerevisiae Aminopeptidase Y (APE3)

CSB-EP339800SVG 3087 mg Ask for price

Recombinant Saccharomyces cerevisiae Aminopeptidase Y (APE3)

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Description: 57-537aa

Recombinant Saccharomyces cerevisiae Acetyl-CoA carboxylase, mitochondrial (HFA1) , partial

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Recombinant Saccharomyces cerevisiae tRNA (carboxymethyluridine (34)-5-O)-methyltransferase

MBS1058361-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1160

Recombinant Saccharomyces cerevisiae tRNA (carboxymethyluridine (34)-5-O)-methyltransferase

MBS1058361-002mgEColi 0.02mg(E-Coli)
EUR 800

Recombinant Saccharomyces cerevisiae tRNA (carboxymethyluridine (34)-5-O)-methyltransferase

MBS1058361-002mgYeast 0.02mg(Yeast)
EUR 950

Recombinant Saccharomyces cerevisiae tRNA (carboxymethyluridine (34)-5-O)-methyltransferase

MBS1058361-01mgEColi 0.1mg(E-Coli)
EUR 960

Recombinant Saccharomyces cerevisiae tRNA (carboxymethyluridine (34)-5-O)-methyltransferase

MBS1058361-01mgYeast 0.1mg(Yeast)
EUR 1110

Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase YUH1 (YUH1)

MBS1090729-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1120

Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase YUH1 (YUH1)

MBS1090729-002mgEColi 0.02mg(E-Coli)
EUR 745

Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase YUH1 (YUH1)

MBS1090729-002mgYeast 0.02mg(Yeast)
EUR 910

Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase YUH1 (YUH1)

MBS1090729-01mgEColi 0.1mg(E-Coli)
EUR 895

Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase YUH1 (YUH1)

MBS1090729-01mgYeast 0.1mg(Yeast)
EUR 1065

Recombinant Saccharomyces cerevisiae Acetyl-CoA carboxylase, mitochondrial (HFA1), partial

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Recombinant Saccharomyces cerevisiae Acetyl-CoA carboxylase, mitochondrial (HFA1), partial

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Recombinant Saccharomyces cerevisiae Acetyl-CoA carboxylase, mitochondrial (HFA1), partial

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Recombinant Saccharomyces cerevisiae Acetyl-CoA carboxylase, mitochondrial (HFA1), partial

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Recombinant Saccharomyces cerevisiae Leucine carboxyl methyltransferase 2 (PPM2) , partial

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Recombinant Saccharomyces cerevisiae Carboxylic acid transporter protein homolog (JEN1) , partial

MBS1198396-1mgEColi 1mg(E-Coli)
EUR 2565

Recombinant Saccharomyces cerevisiae Carboxylic acid transporter protein homolog (JEN1) , partial

MBS1198396-1mgYeast 1mg(Yeast)
EUR 3040

Recombinant Saccharomyces cerevisiae Phosphoenolpyruvate carboxykinase [ATP] (PCK1) , partial

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Recombinant Saccharomyces cerevisiae Phosphoribosylaminoimidazole carboxylase (ADE2) , partial

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Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 4 (DOA4), partial

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Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 4 (DOA4), partial

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Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 5 (UBP5), partial

MBS1136410-1mgEColi 1mg(E-Coli)
EUR 3015

Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 5 (UBP5), partial

MBS1136410-1mgYeast 1mg(Yeast)
EUR 3505

Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 1 (UBP1) , partial

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Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 7 (UBP7) , partial

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Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 4 (DOA4) , partial

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Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 9 (UBP9) , partial

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OPCA01324-100UG - Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1(PYC1) Protein

OPCA01324-100UG 100ug
EUR 668

OPCA01324-20UG - Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1(PYC1) Protein

OPCA01324-20UG 20ug
EUR 449

OPCA01324-500UG - Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1(PYC1) Protein

OPCA01324-500UG 500ug
EUR 1534

Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 11 (UBP11) , partial

MBS1078791-INQUIRE INQUIRE Ask for price

Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 14 (UBP14) , partial

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Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 10 (UBP10) , partial

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Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 15 (UBP15) , partial

MBS1236685-INQUIRE INQUIRE Ask for price

Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 13 (UBP13) , partial

MBS1214042-INQUIRE INQUIRE Ask for price

Recombinant Saccharomyces cerevisiae Ubiquitin carboxyl-terminal hydrolase 12 (UBP12) , partial

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Recombinant Saccharomyces cerevisiae Nicotinate-nucleotide pyrophosphorylase [carboxylating] (BNA6)

MBS1190368-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1175

Recombinant Saccharomyces cerevisiae Nicotinate-nucleotide pyrophosphorylase [carboxylating] (BNA6)

MBS1190368-002mgEColi 0.02mg(E-Coli)
EUR 815

Recombinant Saccharomyces cerevisiae Nicotinate-nucleotide pyrophosphorylase [carboxylating] (BNA6)

MBS1190368-002mgYeast 0.02mg(Yeast)
EUR 965

Recombinant Saccharomyces cerevisiae Nicotinate-nucleotide pyrophosphorylase [carboxylating] (BNA6)

MBS1190368-01mgEColi 0.1mg(E-Coli)
EUR 980

Recombinant Saccharomyces cerevisiae Nicotinate-nucleotide pyrophosphorylase [carboxylating] (BNA6)

MBS1190368-01mgYeast 0.1mg(Yeast)
EUR 1130

Saccharomyces cerevisiae Pyruvate carboxylase 1 (PYC1)

1-CSB-YP319972SVG
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Description: Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1(PYC1),partial expressed in Yeast

Saccharomyces cerevisiae Pyruvate carboxylase 1 (PYC1)

1-CSB-EP319972SVG
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Description: Recombinant Saccharomyces cerevisiae Pyruvate carboxylase 1(PYC1) ,partial expressed in E.coli

Saccharomyces cerevisiae Acetyl-CoA carboxylase (ACC1)

1-CSB-EP2725SVG1
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Description: Recombinant Saccharomyces cerevisiae Acetyl-CoA carboxylase(ACC1),partial expressed in E.coli

Saccharomyces cerevisiae Acetyl-CoA carboxylase (ACC1)

1-CSB-EP2725SVG2
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Description: Recombinant Saccharomyces cerevisiae Acetyl-CoA carboxylase(ACC1),partial expressed in E.coli

Recombinant Saccharomyces cerevisiae Arginase (CAR1)

MBS1012236-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1210

Recombinant Saccharomyces cerevisiae Arginase (CAR1)

MBS1012236-002mgEColi 0.02mg(E-Coli)
EUR 865

Recombinant Saccharomyces cerevisiae Arginase (CAR1)

MBS1012236-002mgYeast 0.02mg(Yeast)
EUR 1000

Recombinant Saccharomyces cerevisiae Arginase (CAR1)

MBS1012236-01mgEColi 0.1mg(E-Coli)
EUR 1040

Recombinant Saccharomyces cerevisiae Arginase (CAR1)

MBS1012236-01mgYeast 0.1mg(Yeast)
EUR 1140

Recombinant Saccharomyces cerevisiae Saccharopepsin (PEP4)

CSB-EP362092SVG 3391 mg Ask for price

Recombinant Saccharomyces cerevisiae Saccharopepsin (PEP4)

CSB-EP362092SVG-100ug 100ug Ask for price
Description: 77-405aa

Recombinant Saccharomyces cerevisiae Saccharopepsin (PEP4)

CSB-EP362092SVG-1mg 1mg Ask for price
Description: 77-405aa

Recombinant Saccharomyces cerevisiae Saccharopepsin (PEP4)

CSB-EP362092SVG-20ug 20ug Ask for price
Description: 77-405aa

Recombinant Saccharomyces cerevisiae Saccharopepsin (PEP4)

CSB-YP362092SVGa4 11452 mg Ask for price

Recombinant Saccharomyces cerevisiae Saccharopepsin (PEP4)

CSB-YP362092SVGa4-100ug 100ug Ask for price
Description: 77-405aa

Recombinant Saccharomyces cerevisiae Saccharopepsin (PEP4)

CSB-YP362092SVGa4-1mg 1mg Ask for price
Description: 77-405aa

Recombinant Saccharomyces cerevisiae Saccharopepsin (PEP4)

CSB-YP362092SVGa4-20ug 20ug Ask for price
Description: 77-405aa

Recombinant Saccharomyces cerevisiae Saccharopepsin (PEP4)

MBS1186522-002mgEColi 0.02mg(E-Coli)
EUR 375

Recombinant Saccharomyces cerevisiae Saccharopepsin (PEP4)

MBS1186522-002mgYeast 0.02mg(Yeast)
EUR 420

Recombinant Saccharomyces cerevisiae Saccharopepsin (PEP4)

MBS1186522-01mgEColi 0.1mg(E-Coli)
EUR 635

Recombinant Saccharomyces cerevisiae Saccharopepsin (PEP4)

MBS1186522-01mgYeast 0.1mg(Yeast)
EUR 695

Recombinant Saccharomyces cerevisiae Saccharopepsin (PEP4)

MBS1186522-05mgYeast 0.5mg(Yeast)
EUR 1505

Recombinant Saccharomyces cerevisiae Actin (ACT1)

MBS1019031-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1250

Recombinant Saccharomyces cerevisiae Actin (ACT1)

MBS1019031-002mgEColi 0.02mg(E-Coli)
EUR 915

Recombinant Saccharomyces cerevisiae Actin (ACT1)

MBS1019031-002mgYeast 0.02mg(Yeast)
EUR 1040

Recombinant Saccharomyces cerevisiae Actin (ACT1)

MBS1019031-01mgEColi 0.1mg(E-Coli)
EUR 1100

Recombinant Saccharomyces cerevisiae Actin (ACT1)

MBS1019031-01mgYeast 0.1mg(Yeast)
EUR 1185

Recombinant Saccharomyces cerevisiae Actin (ACT1)

CSB-EP001205SVG 11337 mg Ask for price

Recombinant Saccharomyces cerevisiae Actin (ACT1)

CSB-EP001205SVG-100ug 100ug Ask for price
Description: 1-375aa

Recombinant Saccharomyces cerevisiae Actin (ACT1)

CSB-EP001205SVG-1mg 1mg Ask for price
Description: 1-375aa

Recombinant Saccharomyces cerevisiae Actin (ACT1)

CSB-EP001205SVG-20ug 20ug Ask for price
Description: 1-375aa

Recombinant Saccharomyces cerevisiae She2p (SHE2)

MBS1264805-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1130

Recombinant Saccharomyces cerevisiae She2p (SHE2)

MBS1264805-002mgEColi 0.02mg(E-Coli)
EUR 755

Recombinant Saccharomyces cerevisiae She2p (SHE2)

MBS1264805-002mgYeast 0.02mg(Yeast)
EUR 915

Recombinant Saccharomyces cerevisiae She2p (SHE2)

MBS1264805-01mgEColi 0.1mg(E-Coli)
EUR 910

Recombinant Saccharomyces cerevisiae She2p (SHE2)

MBS1264805-01mgYeast 0.1mg(Yeast)
EUR 1075

Recombinant Saccharomyces cerevisiae Peflin (PEF1)

MBS1209695-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1210

Recombinant Saccharomyces cerevisiae Peflin (PEF1)

MBS1209695-002mgEColi 0.02mg(E-Coli)
EUR 865

Recombinant Saccharomyces cerevisiae Peflin (PEF1)

MBS1209695-002mgYeast 0.02mg(Yeast)
EUR 1000

Recombinant Saccharomyces cerevisiae Peflin (PEF1)

MBS1209695-01mgEColi 0.1mg(E-Coli)
EUR 1040

Recombinant Saccharomyces cerevisiae Peflin (PEF1)

MBS1209695-01mgYeast 0.1mg(Yeast)
EUR 1140

Recombinant Saccharomyces cerevisiae Zuotin (ZUO1)

MBS1157863-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1300

Recombinant Saccharomyces cerevisiae Zuotin (ZUO1)

MBS1157863-002mgEColi 0.02mg(E-Coli)
EUR 985

Recombinant Saccharomyces cerevisiae Zuotin (ZUO1)

MBS1157863-002mgYeast 0.02mg(Yeast)
EUR 1095

Recombinant Saccharomyces cerevisiae Zuotin (ZUO1)

MBS1157863-01mgEColi 0.1mg(E-Coli)
EUR 1150

Recombinant Saccharomyces cerevisiae Zuotin (ZUO1)

MBS1157863-01mgYeast 0.1mg(Yeast)
EUR 1250

Recombinant Saccharomyces Cerevisiae GSR Protein

VAng-Wyb4133-500g 500 µg
EUR 3237.6
Description: Saccharomyces Cerevisiae Glutathione Reductase, recombinant protein.

Recombinant Saccharomyces Cerevisiae TXN Protein

VAng-Wyb6094-1mg 1 mg
EUR 8420.4
Description: Saccharomyces Cerevisiae Thioredoxin, recombinant protein.

Recombinant Saccharomyces Cerevisiae TXN Protein

VAng-Wyb6094-500g 500 µg
EUR 4965.6
Description: Saccharomyces Cerevisiae Thioredoxin, recombinant protein.

Recombinant Saccharomyces cerevisiae KEX2 Protein

KEX2-02S 50ug
EUR 127.2
Description: Dry powder stored below -15℃, stable for 24 months. After dissolving, it is stored in sub-packaging below -15℃ and stabilized by freezing and thawing repeatedly for 3 times. It can be stored at 2~8℃ for 3 days after dissolution.

Recombinant Saccharomyces cerevisiae Securin (PDS1)

MBS1010083-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1245

Recombinant Saccharomyces cerevisiae Securin (PDS1)

MBS1010083-002mgEColi 0.02mg(E-Coli)
EUR 910

Recombinant Saccharomyces cerevisiae Securin (PDS1)

MBS1010083-002mgYeast 0.02mg(Yeast)
EUR 1040

Recombinant Saccharomyces cerevisiae Securin (PDS1)

MBS1010083-01mgEColi 0.1mg(E-Coli)
EUR 1100

Recombinant Saccharomyces cerevisiae Securin (PDS1)

MBS1010083-01mgYeast 0.1mg(Yeast)
EUR 1180

Recombinant Saccharomyces Cerevisiae DSDA Protein

VAng-Wyb4554-200g 200 µg
EUR 2904
Description: Saccharomyces Cerevisiae (strain ATCC 204508 / S288c) D-Serine Dehydratase, recombinant protein.

Recombinant Saccharomyces Cerevisiae GAS2 Protein

VAng-Wyb4670-inquire inquire Ask for price
Description: Saccharomyces Cerevisiae Growth Arrest-Specific 2 protein, recombinant protein.

Recombinant Saccharomyces Cerevisiae GLC8 Protein

VAng-Wyb4699-100g 100 µg
EUR 4320
Description: Saccharomyces Cerevisiae Glc8p, recombinant protein.

Recombinant Saccharomyces Cerevisiae TXN2 Protein

VAng-Wyb6098-500g 500 µg
EUR 4965.6
Description: Saccharomyces Cerevisiae Thioredoxin 2, recombinant protein.

Recombinant Saccharomyces Cerevisiae CAR2 Protein (aa 1-424) [His]

VAng-Wyb4356-1mg 1 mg
EUR 5876.4
Description: Saccharomyces Cerevisiae (strain ATCC 204508 / S288c) Ornithine Aminotransferase, recombinant protein.

Recombinant Saccharomyces cerevisiae Profilin (PFY1)

MBS1009499-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1050

Recombinant Saccharomyces cerevisiae Profilin (PFY1)

MBS1009499-002mgEColi 0.02mg(E-Coli)
EUR 630

Recombinant Saccharomyces cerevisiae Profilin (PFY1)

MBS1009499-002mgYeast 0.02mg(Yeast)
EUR 800

Recombinant Saccharomyces cerevisiae Profilin (PFY1)

MBS1009499-01mgEColi 0.1mg(E-Coli)
EUR 730

Recombinant Saccharomyces cerevisiae Profilin (PFY1)

MBS1009499-01mgYeast 0.1mg(Yeast)
EUR 935

Recombinant Saccharomyces Cerevisiae TIM14 Protein

VAng-Wyb6025-1mg 1 mg
EUR 37512
Description: Saccharomyces Cerevisiae TIM14, recombinant protein.

Recombinant Saccharomyces Cerevisiae TIM14 Protein

VAng-Wyb6025-500g 500 µg
EUR 24284.4
Description: Saccharomyces Cerevisiae TIM14, recombinant protein.

Recombinant Saccharomyces Cerevisiae TIM14 Protein

VAng-Wyb6025-50g 50 µg
EUR 7365.6
Description: Saccharomyces Cerevisiae TIM14, recombinant protein.

Recombinant Saccharomyces Cerevisiae TIM16 Protein

VAng-Wyb6026-1mg 1 mg
EUR 37512
Description: Saccharomyces Cerevisiae TIM16, recombinant protein.
As well as, the diploma of correlation between pro-inflammatory cytokines and microbiota was as follows: interleukin (IL)-1β > IL-8 > IL-6 > tumor necrosis factor-α To summarize, EWPs contributed to the alleviation of colitis signs and the intestinal harm via anti-inflammatory results, restore of intestinal mucosa, and modulation of intestine microbiota.

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